Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Gas chromatographic enantiomer separation on single and mixed cyclodextrin derivative chiral stationary phases [PDF]
Capillary gas chromatographic enantiomer separation of some polar compounds, including alpha-phenylethylamine, styrene oxide, pyrethroid insecticides and other carboxylates, was investigated on modified cyclodextrin (CD) chiral stationary phases.
Zhu, DQ, Zhou, LM, Wang, QH, Nie, MY
core
Conversion of polar and non-polar algae oil lipids to fatty acid methyl esters with solid acid catalysts:A model compound study [PDF]
Bio-based fuels are becoming more and more important due to the depleting fossil resources. The production of biodiesel from algae oil is challenging compared to terrestrial vegetable oils, as algae oil consists of polar fatty acids, such as ...
Munter, Tony +2 more
core +1 more source
5-Azido-4-dimethylamino-1-methyl-1,2,4-triazolium Hexafluoridophosphate and Derivatives
5-Azido-4-(dimethylamino)-1-methyl-1,2,4-triazolium hexafluoridophosphate was synthesized from the corresponding 5-bromo compound with NaN3. Reaction with bicyclo[2.2.1]hept-2-ene yielded a tricyclic aziridine, addition of an N-heterocyclic carbene ...
Gerhard Laus +2 more
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Quantitative predictions on auxin-induced polar distribution of PIN proteins during vein formation in leaves [PDF]
The dynamic patterning of the plant hormone auxin and its efflux facilitator the PIN protein are the key regulator for the spatial and temporal organization of plant development.
Frey, Erwin +3 more
core +1 more source
The novel benzanthrone derivative, 2-bromo-3-aminobenzo[de]anthracene-7-one (2-Br-3-NH2BA), was synthesized and extensively characterized to investigate its photophysical behavior in various solvents.
Emmanuel Karungani +7 more
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Sensitivity analysis for multidisciplinary design optmization [PDF]
When designing a complex industrial product, the designer often has to optimise simultaneously multiple conflicting criteria. Such a problem does not usually have a unique solution, but a set of non-dominated solutions known as Pareto solutions.
Maginot, Jeremy
core
VEGETATION CHANGE DETECTION USING LANDSAT DATA IN NORTHERN FINLAND : A TEST CASE USING SMOOTHING AND LAPLACIAN FILTERING (15th Symposium on Polar Biology) [PDF]
P(論文)It has been predicted that some boreal tree species would migrate north several hundred meters annually in response to the predicted global warming due to doubling of CO_2 by the middle of the next century.
/ タナカ, ノブヒコ +4 more
core +2 more sources

