Results 51 to 60 of about 76,947 (261)
Herein, liquid crystalline derivatives based on palmitate, oleate, and linoleate moieties with azomethine cores were synthesized, and their physical, chemical, optical, and photophysical properties were investigated in detail. The mesomorphic activity of
Salma A. Al-Zahrani +5 more
doaj +1 more source
Polarization and reprogramming of myeloid-derived suppressor cells [PDF]
Myeloid-derived suppressor cells (MDSC) have recently emerged as one of the central regulators of the immune system. In recent years, interest in understanding MDSC biology and applying MDSC for therapeutic purpose has exploded exponentially. Despite recent progress in MDSC biology, the mechanisms underlying MDSC development from expansion and ...
Wen-Chin, Yang +3 more
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Segmentation of PMSE Data Using Random Forests
EISCAT VHF radar data are used for observing, monitoring, and understanding Earth’s upper atmosphere. This paper presents an approach to segment Polar Mesospheric Summer Echoes (PMSE) from datasets obtained from EISCAT VHF radar data. The data consist of
Dorota Jozwicki +3 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
L^p inequalities for polar derivatives of polynomials [PDF]
Let \(p(z)=a_0+a_1z+ \cdots+ a_nz^n\) be a polynomial of degree \(n\) and let for fixed \(\alpha\in\mathbb{C}\) \[ D_\alpha p(z):= np(z)+(\alpha-z)p'(z) \] denote the polar derivative of \(p(z)\) with respect to \(\alpha\). In this paper some inequalities for such polar derivatives are presented. In particular it is proved: Theorem.
Govil, N. K., Nyuydinkong, G.
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Self-assembly and semiconductivity of an oligothiophene supergelator
A bis(trialkoxybenzamide)-functionalized quaterthiophene derivative was synthesized and its self-assembly properties in solution were studied. In non-polar solvents such as cyclohexane, this quaterthiophene π-system formed fibril aggregates with an H ...
Pampa Pratihar +6 more
doaj +1 more source
N-acylhydrazone compounds have two isomers, E/cis and E/trans, in polar solvents. In this work, 1H and 13C nuclear magnetic resonance (NMR) signals, coupling constants (J), and the spatial structures of the two isomers (E/cis and E/trans) of a novel ...
LI Ying-jun +5 more
doaj +1 more source
1HNMR OF PYRAZOLES: EFFECT OF INTERACTION OF CARBAMOYL GROUP WITH ADJACENT CENTERS ON THE CHEMICAL SHIFTS OF CONCERNED PROTONS [PDF]
The 1HNMR of a series of constitutional isomers of dimethylpyrazole carboxamides revealed the contribution of p and/or n-electrons in deshielding protons a- to CONHR group.
Abd-El-Hamid Ahmed +2 more
doaj +1 more source

