Results 91 to 100 of about 1,091,930 (313)

Dietary polar lipids alter gut microbiota composition and anti-inflammatory lipid mediator profiles in weaned piglets

open access: yesAnimal Nutriomics
Dairy polar lipids have demonstrated anti-inflammatory properties and protective effects on intestinal integrity, potentially mitigating the adverse impacts of weaning in piglets by modulating microbiota composition and intermediary metabolism.
Rayllana Larsen   +10 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Review of 100 facts: polar lands; 365 penguins; Amazing Arctic & Antarctic projects you can build yourself; Apun: the Arctic snow; Matthew Henson: the quest for the North Pole; Polar bears in danger; Polar regions; Race to the South Poleetc.

open access: yes, 2010
The polar regions have captured the world’s attention, and children’s book authors and publishers are no exception. These dozen titles are just a sample of the bucketload of polar-themed children’s books that have been published during the last couple of
Goldman, Helle
core   +1 more source

The Many Faces of Amphipathic Helices

open access: yesBiomolecules, 2018
Amphipathic helices (AHs), a secondary feature found in many proteins, are defined by their structure and by the segregation of hydrophobic and polar residues between two faces of the helix.
Manuel Giménez-Andrés   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Aerial strip surveys of polar bears in the Barents Sea

open access: yes, 1990
Aerial strip surveys of polar bears in the Barents Sea were performed by helicopter in winter 1987. The number of bears within 100 m on each side of the helicopter was counted. A total of 263.6 km2 was surveyed and 21 bears were counted.
Wiig, Øystein, Bakken, Vidar
core   +1 more source

Multiple-stressor effects in an apex predator: combined influence of pollutants and sea ice decline on lipid metabolism in polar bears

open access: yesScientific Reports, 2017
There is growing evidence from experimental and human epidemiological studies that many pollutants can disrupt lipid metabolism. In Arctic wildlife, the occurrence of such compounds could have serious consequences for seasonal feeders.
Sabrina Tartu   +11 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Revisiting perceptions and evolving culture: a community dialogue on women in polar research

open access: yes, 2018
Women have made outstanding contributions to polar research in recent decades, though full engagement may be hindered by persistent inequities, including notably the prevalence of workplace harassment.
Seag, M.   +3 more
core  

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