Results 31 to 40 of about 2,970,939 (235)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

A fast cold-start method of GPS receiver based on satellite orbit prediction

open access: yesMATEC Web of Conferences, 2018
Time to first fix (TTFF) is one of the crucial indicators to evaluate the performance of a GPS receiver. In this paper, an orbit prediction algorithm to reduce the TTFF of GPS receivers without a network connection is presented.
Yang Ruihong   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Human motion prediction for navigation of a mobile robot [PDF]

open access: yes, 2011
Human motion prediction is an important feature to improve the path planning of mobile robots. An exact prediction of the pedestrian trajectory allows not only to avoid them safely but to induce also socially acceptable motions.
Schmiedhofer , Klaus
core  

Polar Research’s referees

open access: yes, 2010
It is once again time to thank all the scientists— not only those whose names are printed on the following pages—who have kindly served as referees for Polar Research during the last couple of ...
Goldman, Helle V.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Demonstration and Evaluation of 3D Winds Generated by Tracking Features in Moisture and Ozone Fields Derived from AIRS Sounding Retrievals

open access: yesRemote Sensing, 2019
For more than 15 years, polar winds from the Moderate Resolution Imaging Spectroradiometer (MODIS) imagery have been generated by the National Oceanic and Atmospheric Administration (NOAA) and the Cooperative Institute for Meteorological Satellite ...
David Santek   +2 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Ichnodiversity in the eastern Canadian Arctic in the context of polar microbioerosion patterns

open access: yes, 2022
Studies of marine microbioerosion in polar environments are scarce. They include our recent investigations of bioerosion traces preserved in sessile balanid skeletons from the Arctic Svalbard archipelago and the Antarctic Ross Sea.
Wisshak, Max   +4 more
core   +1 more source

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