Results 31 to 40 of about 2,970,939 (235)
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
A fast cold-start method of GPS receiver based on satellite orbit prediction
Time to first fix (TTFF) is one of the crucial indicators to evaluate the performance of a GPS receiver. In this paper, an orbit prediction algorithm to reduce the TTFF of GPS receivers without a network connection is presented.
Yang Ruihong +3 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Human motion prediction for navigation of a mobile robot [PDF]
Human motion prediction is an important feature to improve the path planning of mobile robots. An exact prediction of the pedestrian trajectory allows not only to avoid them safely but to induce also socially acceptable motions.
Schmiedhofer , Klaus
core
It is once again time to thank all the scientists— not only those whose names are printed on the following pages—who have kindly served as referees for Polar Research during the last couple of ...
Goldman, Helle V.
core +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
For more than 15 years, polar winds from the Moderate Resolution Imaging Spectroradiometer (MODIS) imagery have been generated by the National Oceanic and Atmospheric Administration (NOAA) and the Cooperative Institute for Meteorological Satellite ...
David Santek +2 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Ichnodiversity in the eastern Canadian Arctic in the context of polar microbioerosion patterns
Studies of marine microbioerosion in polar environments are scarce. They include our recent investigations of bioerosion traces preserved in sessile balanid skeletons from the Arctic Svalbard archipelago and the Antarctic Ross Sea.
Wisshak, Max +4 more
core +1 more source

