Results 71 to 80 of about 7,387,440 (343)

Polarization-Independent Two-Layer Grating With Five-Port Splitting Output Under Normal Incidence

IEEE Photonics Journal, 2020
In this paper, we report a two-layer five-port diffraction grating by a polarization-independent design under normal incidence. To be different from conventional five-port gratings, initially, we design a novel two-layer grating with operation in ...
Bowen Gong, Huiying Wen, Hongtao Li
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Synthesis of metasurface-enabled broadband polarization-independent light structuring

Structured light beams have attracted significant interest due to their versatile spatial or spatiotemporal configurations, which can potentially transform various real-world applications not achievable using conventional Gaussian beams.
Mehmood, Muhammad Qasim, Tauqeer, Tauseef, Butt, Naureen, Mahmood, Nasir   +3 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Polarization singularities in the clear sky

, 2004
Ideas from singularity theory provide a simple account of the pattern of polarization directions in daylight. The singularities (two near the Sun and two near the anti-Sun) are points in the sky where the polarization line pattern has index +1/2 and the ...
R L Lee, Dennis, MR, Berry, MV, Lee, Jr, R.L., M R Dennis, M V Berry, Lee Jr, RL, Dennis, M.R., Berry, M V, Dennis, M R; id_orcid, Lee, R L, Berry, M.V.   +11 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A compact two-dimensional grating coupler used as a polarization splitter

, 2003
We demonstrate a novel polarization splitter based on a two-dimensional grating etched in a silicon-on-insulator waveguide. The device couples orthogonal modes from a single-mode optical fiber into identical modes of two planar ridge waveguides.
De La Rue, RM, Baets, Roel, De La Rue, R.M., Baets, R, FRANDSEN, L, Tailaert, D., Frandsen, LH, Borel, Peter Ingo, BOREL, P, Taillaert, Dik, DE LA RUE, R, Rue, R.M. de la, Taillaert, Dirk, Frandsen, L.H., Taillaert, D, Chong, H, Chong, H., Baets, R., Borel, PI, Frandsen, Lars Hagedorn, Taillaert, D., Borel, P.I.   +21 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Twisted Hi-Bi fiber DFB lasers with controllable output polarization [PDF]

, 2012
We demonstrate that single polarization, hi-bi fiber DFB lasers are in general characterized by elliptical state of polarization, due to the in-built fiber birefringence axis rotation.
Richard Wilmshurst, Louise M. B. Walker, Michalis N. Zervas, Wilmshurst, R., Zervas, M.N., Walker, L.M.B.   +5 more
core   +1 more source