Results 81 to 90 of about 4,434,939 (302)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Simultaneous Beat-Length Measurement of a Polarization-Maintaining Few-Mode Fiber

open access: yesIEEE Photonics Journal, 2019
Based on the polarization interference technique, we propose a modified method for simultaneously measuring the beat length of all guided modes in a polarization-maintaining few-mode fiber (PM-FMF).
Yaping Liu   +5 more
doaj   +1 more source

Highly coherent supercontinuum generation in a polarization-maintaining CS2-core photonic crystal fiber.

open access: yesApplied Optics, 2019
In this paper, we design a polarization-maintaining CS2-core photonic crystal fiber (PM-CCPCF). The two air holes in the x direction are infiltrated with C2H5OH in order to introduce birefringence.
Feng Xu   +9 more
semanticscholar   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

RF Interferometry Measurement of Beat Length in Polarization-Maintaining Fiber

open access: yesIEEE Photonics Journal, 2020
A microwave photonics interferometric (MWPI) method for measuring the beat length in high birefringence polarization-maintaining fiber (PMF) is proposed.
Liang Peng   +3 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

All-polarization-maintaining dual-wavelength mode-locked fiber laser based on Sagnac loop filter.

open access: yesOptics Express, 2018
We demonstrate an all polarization-maintaining (PM) fiber based dual-wavelength mode-locked Er-fiber laser. A nonlinear amplifying loop mirror (NALM) with an intracavity nonreciprocal phase shifter is used for self-started mode-locking.
Run-Min Li   +6 more
semanticscholar   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Ontology‐Aligned Structuring and Reuse of Multimodal Materials Data and Workflows Toward Automatic Reproduction

open access: yesAdvanced Engineering Materials, EarlyView.
Reproduction of stacking fault energy calculations from literature with a semi‐automated large language model‐assisted extraction procedure: extraction of simulation protocol, atomistic structures, computational parameters, and reported results, ontology alignment, knowledge graph construction and, finally, recomputation forvalidation.
Sepideh Baghaee Ravari   +5 more
wiley   +1 more source

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