Results 61 to 70 of about 4,434,939 (302)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

All-polarization-maintaining Er-doped dual comb fiber laser using single-wall carbon nanotubes.

open access: yesOptics Express, 2019
We demonstrated a bi-directional, Er-doped dual comb fiber laser consisting of all-polarization-maintaining fiber devices. Polyimide films in which single-wall carbon nanotubes (SWNTs) were dispersed were used as the in-line saturable absorber.
Shuto Saito   +5 more
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Design of Hollow-Core Anti-Resonant Fibers Supporting Few Weakly Coupled Polarization-Maintaining Modes

open access: yesPhotonics
A nested semi-tube hollow-core anti-resonant fiber (HC-ARF) that can support the high-purity transmission of a few polarization-maintaining modes is designed in this paper.
Linxuan Zong, Jiayao Cheng, Yueyu Xiao
doaj   +1 more source

Ultra low-noise coherent supercontinuum amplification and compression below 100 fs in an all-fiber polarization-maintaining thulium fiber amplifier.

open access: yesOptics Express, 2019
We report an ultra-low noise, polarization-maintaining, ultrafast Thulium-doped all-fiber chirped pulse amplifier, seeded by a polarized all-normal dispersion (ANDi) supercontinuum (SC) driven by an ultrafast Erbium-fiber laser. The system comprises only
Anupamaa Rampur   +8 more
semanticscholar   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Research Progress on All-Polarization-Maintaining Mode-Locked Fiber Lasers

open access: yesPhotonics
This article reviews the research progress of all-polarization-maintaining mode-locked fiber lasers. Owing to their excellent resistance to environmental interference and high stability, all-polarization-maintaining mode-locked fiber lasers hold ...
Ying Wang, Minghong Wang
doaj   +1 more source

Compact, High-Performance All-Polarization-Maintaining Er: Fiber Frequency Comb With Single Fiber Actuator

open access: yesIEEE Photonics Journal, 2020
The large volume and weak environmental adaptability of fiber optical frequency combs (OFCs) have become the main obstacles for their applications in various fields.
Yajun Cai   +7 more
doaj   +1 more source

All polarization-maintaining fiber laser architecture for robust femtosecond pulse generation

open access: yes, 2017
We report on a novel architecture for robust mode-locked femtosecond fiber lasers using a nonlinear optical loop mirror with all polarization-maintaining fibers.
W. Hänsel   +10 more
semanticscholar   +1 more source

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