Results 61 to 70 of about 610,284 (295)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Polarization-Independent Fiber-Optic SPR Sensor

Sensors, 2018
Fiber-optic surface plasmon resonance (SPR) sensors possess the advantages of small size, flexible, allowing for a smaller sample volume, easy to be integrated, and high sensitivity. They have been intensively developed in recent decades.
Songquan Li, Laixu Gao, Changwei Zou, Wei Xie, Yong Wei, Canxin Tian, Zesong Wang, Feng Liang, Yanxiong Xiang, Qian Yang   +9 more
doaj   +1 more source

Double-lepton polarization asymmetries in the (B -> K l^+ l^-) decay beyond the Standard Model

, 2003
General expressions for the double-lepton polarizations in the (B -> K l^+ l^-) decay are obtained, using model independent effective Hamiltonian, including all possible interactions.
66, Aliev, Aliev, Aliev, Bensalem, Burdman, Choudhury, Choudhury, Choudhury, Choudhury, Collaboration, Collaboration, Gaur, Ishikawa, Krüger, M. Savcí, T. M. Aliev, V. Bashiry   +17 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

A Study on Optimal Design of Polarization-Independent Magneto-Metasurface Isolators Based on Multi-Material Topology Optimization

IEEE Photonics Journal
Metasurface has attracted a lot of attentions because they can realize properties that cannot be achieved with ordinary materials and are easy to be fabricated using established fabrication processes. In this paper, in order to design metasurface without
Mio Taniguchi, Akito Iguchi, Yasuhide Tsuji   +2 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Polarization-Independent All-Optical Regenerator for DPSK Data

Photonics, 2014
We demonstrate polarization-independent simultaneous all-optical phase-preserving amplitude regeneration and wavelength conversion of NRZ differential phase shift keying (DPSK) data by four-wave mixing (FWM) in a semiconductor optical amplifier (SOA ...
Valeria Vercesi, Claudio Porzi, Giampiero Contestabile, Antonella Bogoni   +3 more
doaj   +1 more source

Polarization independent lattice-coupled terahertz toroidal excitation

Journal of Physics D: Applied Physics, 2023
Abstract The toroidal dipole excitation is important for metamaterial research because of its low-loss attribute. In this study, we demonstrate numerically and experimentally, a unique toroidal metasurface that modulates a broad resonance into a sharp mode, independent of the polarization of the incident terahertz (THz) radiation, by ...
Angana Bhattacharya, Bhagwat Singh Chouhan, Rajan Singh, Bhairov K Bhowmik, Gagan Kumar   +4 more
openaire   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source