Results 81 to 90 of about 610,284 (295)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A Hybrid-Plasmonic-Waveguide-Based Polarization-Independent Directional Coupler

IEEE Access, 2020
In optical interconnection field, inconsistent coupling behaviors of TE and TM modes may cause abnormal operation. Therefore, it is very significant to implement a polarization-independent directional coupler.
Li Zhang, Can Pan, Dezheng Zeng, Yanzhao Yang, Yatao Yang, Junxian Ma   +5 more
doaj   +1 more source

Interfacial effects on the polarization of $BiFeO_{3}$ films

, 2009
By considering an interfacial layer between the electrode and the $BiFeO_{3}$($BFO$) layer, the polarization and the hysteresis behavior of $BFO$ film are simulated.
Cho, Eerenstein, Eerenstein, Fischer, Habouti, Ho Kim, Jiang, Lee, Lee, Li, Liu, Ma, Miller, Tao Pan, Tsui, Venevtsev, Yin-Zhong Wu, Zhang, Zhen-Ya Li   +18 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Polarization-Insensitive Lithium Niobate-on-Insulator Interferometer

Micromachines
The key components of a polarization-independent electro-optic (EO) interferometer, including the beam splitter, mode converter, and directional coupler, are designed based on a lithium niobate (LN) platform on an integrated insulator to ensure high ...
Jiali Liao, Linke Liu, Yanling Sun, Zihao Wang, Wei Li, Jinrong Lan, Lin Ma, Zhenzhong Lu   +7 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Quantum Entanglement and the Two-Photon Stokes Parameters

, 2001
A formalism for two-photon Stokes parameters is introduced to describe the polarization entanglement of photon pairs. This leads to the definition of a degree of two-photon polarization, which describes the extent to which the two photons act as a pair ...
Abouraddy, Abouraddy, Alexander V. Sergienko, Ayman F. Abouraddy, Bahaa E.A. Saleh, Born, Boschi, Bouwmeester, Branning, Jaeger, Jaeger, Jordan, Klyshko, Klyshko, Lehner, Malvin C. Teich, McMaster, O'Neill, Pauli, Peres, Perina, Popescu, Sakurai, Saleh, Schrödinger, Sergienko, Shi, Shurcliff, Stokes, Werner, Wootters   +30 more
core   +1 more source

Vacuum polarization energy of the Shifman-Voloshin soliton [PDF]

, 2018
We compute the vacuum polarization energy of soliton configurations in a model with two scalar fields in one space dimension using spectral methods. The second field represents an extension of the conventional $\phi^4$ kink soliton model.
Graham, N., Weigel, H.
core   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Faraday scaling and the Bicep2 observations

, 2014
As repeatedly speculated in the past, the linear polarization of the Cosmic Microwave Background can be rotated via the Faraday effect. An economic explanation of the recent Bicep2 observations, not relying on long-wavelength tensor modes of the geometry,
Giovannini, Massimo
core   +1 more source