Results 41 to 50 of about 16,532 (301)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Picrosirius enhanced polarizing microscopy of TMJ-OA.

open access: yes, 2019
Changes in the organization and orientation of the superficial layer extracellular matrix associated with the progression of TMJ-OA. Reconstructions of a mouse cranium and mandible defining the mesiodistal axis, the mediolateral axis, and orientation of ...
David A. Reed (6397355)   +4 more
core   +1 more source

High-resolution cell outline segmentation and tracking from phase-contrast microscopy images [PDF]

open access: yes, 2011
Accurate extraction of cell outlines from microscopy images is essential for analysing the dynamics of migrating cells. Phase-contrast microscopy is one of the most common and convenient imaging modalities for observing cell motility because it does not ...
Verkhovsky, Alexander B   +13 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Study of particle aggregation in polymer solution by polarizing microscopy

open access: yes, 2022
Pomocí orálně disperzních filmů (ODF) budeme sledovat agregaci a sedimentaci částic v polymerním roztoku. Ty jsou jedny z klíčových dějů, které negativně ovlivňují homogenitu roztoku, která je důležitá pro přípravu kompozitních materiálů obsahující ...
Paličková, Dana
core  

Rheology of the lamellar liquid-crystalline phase in polyethoxylated alcohol/water/heptane systems.

open access: yesGrasas y Aceites, 2005
Linear viscoelastic tests as well as transient and steady flow experiments were carried out on lamellar liquid crystalline samples of poly (oxyethylene) alcohol/water/heptane systems. The effect of surfactant and heptane concentrations on the rheological
F. Cordobés, J. M. Franco, C. Gallegos
doaj   +1 more source

A Young Boy with Brittle Hair

open access: yesCase Reports in Dermatology, 2022
Trichothiodystrophy (TTD) is a rare multisystem disorder with an autosomal recessive mode of inheritance. TTD presentations vary from only hair abnormalities like brittle, fragile hair to physical and mental retardation.
Nassim Tootoonchi   +6 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Evaluation of Fibrotic Changes in OSMF:A Retrospective Study Using Special Stains and Polarizing Microscopy

open access: yes, 2017
<p><strong>Background:</strong> Oral submucous fibrosis (OSMF), a potentially malignant oral disorder has the highest rate of malignant transformation of about 7-13%.
Nadeem Jeddy, Parvez Ikram
core   +1 more source

Synthesis and mesomorphic properties of calamitic malonates and cyanoacetates tethered to 4-cyanobiphenyls

open access: yesBeilstein Journal of Organic Chemistry, 2012
4-Cyano-1,1'-biphenyl derivatives bearing ω-hydroxyalkyl substituents were reacted with methyl 3-chloro-3-oxopropionate or cyanoacetic acid, giving liquid-crystalline linear malonates and cyanoacetates. These compounds formed monotropic nematic phases at
Katharina C. Kress   +4 more
doaj   +1 more source

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