Toward Biology-Driven Surveillance After Endometrial Cancer Treatment: A Molecular-Clinical Framework Integrating Recurrence Phenotype. [PDF]
Szatkowski W, Glanowska-Nawrat I.
europepmc +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Steerable versus Conventional flexible and navigable suction ureteral access sheath (FANS) flexible Ureteroscopy for Lower Pole stones Treatment: study protocol for a multicentre, randomised superiority trial (SCULPT trial). [PDF]
Yuen SKK +30 more
europepmc +1 more source
Active vibration control for asymmetric systems by pole assignment
Most structural systems are symmetric and naturally stable but some are asymmetric and prone to instability. The asymmetric system is defined by a non-symmetric matrix and generated by a non-conservative force.
Ariyatanapol, Rittirong
core
Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh +7 more
wiley +1 more source
Distinct mutational landscape and clonal evolution of POLE-mutated endometrial cancer: geographic variation and insights into multiple classifier status. [PDF]
Song Y +5 more
europepmc +1 more source
Parameterization of state feedback gains for pole assignment
The pole assignment problem has been subject for research for a long time. For single-input single-output systems this problem is well understood but for multi-input multi-output systems the pole assignment problem is more complex.
Norlander, Hans
core
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Genomic and Transcriptomic Analysis of High-Grade Endometrial Carcinoma Reveals Biological Heterogeneity and Molecular Classification Challenges. [PDF]
Kawazu M +22 more
europepmc +1 more source
High‐throughput screening led to the identification of 67 Z‐scheme heterojunctions (comprising 2D magnetic transition metal halides and non‐magnetic transition metal chalcogenides). For CrI3/MoTe2 and CrI3/WTe2, electronic structure analysis demonstrated that synergistic crystallographic point group and built‐in electric field effects generate a ...
Hongyang Ren +8 more
wiley +1 more source

