Results 21 to 30 of about 593 (123)
Isoenzimas do CYP450 e biotransformação de drogas
Acta Scientiarum: Biological Sciences, 2008 A administração de uma droga em seres humanos, muitas vezes, gera uma resposta farmacológica inesperada, que pode ser determinada pela concentração plasmática anormal da mesma, podendo produzir, como conseqüência, vários efeitos indesejáveis. A avaliação
Elisabeth Aparecida Audi +1 more
doaj +1 more source
Contexto clínico y genético de la obesidad: un complejo mundo por dilucidar
Anales de la Facultad de Medicina, 2017 La Organización Mundial de la Salud define la obesidad como una acumulación excesiva de grasa que constituye un riesgo para la salud; es un problema de Salud Pública.
Laura Isabel Jaramillo-Jaramillo +2 more
doaj +1 more source
Diversitas Journal, 2023 O polimorfismo do gene LDLR (receptor de LDL colesterol) está associado com alterações lipídicas, como a hipercolesterolemia familiar (HF), provocada por mutações nos genes que produzem as proteínas catabólicas e de captação do LDLR.
Fábio Castro Ferreira +5 more
doaj +1 more source
Assessing differences among elasmobranch nurseries to aid conservation based on a genomics framework
Conservation Biology, EarlyView.Abstract Elasmobranch nurseries often differ in environmental conditions, demographics, and use patterns. These differences affect the distribution of genetic variation among nurseries. However, conservation and management strategies often fail to account for such differences because they are difficult to characterize.
Dominic G. Swift +8 more
wiley +1 more source
Equine Veterinary Journal, Volume 57, Issue 4, Page 943-952, July 2025.Abstract Background Equine recurrent laryngeal neuropathy (RLN) is an economically important upper respiratory tract (URT) disease with a genetic contribution to risk, but genetic variants independent of height have not been identified for Thoroughbreds.
Charlotte L. McGivney +8 more
wiley +1 more source
Ecology and Evolution, Volume 15, Issue 5, May 2025.We have developed a genome‐enabled single nucleotide polymorphism (SNP) panel for use in jaguar geographic traceability, individual identification, kinship, and sexing. Our panel, named “Jag‐SNP”, comprises 459 SNPs selected from an initial pool of 13,373,949 markers based on the inter‐biome FST, followed by rigorous filtering and addition of eight sex‐
Gabriele Zenato Lazzari +6 more
wiley +1 more source
Sequencing vs. amplification for the estimation of allele dosages in sugarcane (Saccharum spp.)
Applications in Plant Sciences, Volume 12, Issue 5, September-October 2024.Abstract Premise Detecting single‐nucleotide polymorphisms (SNPs) in a cost‐effective way is fundamental in any plant breeding pipeline. Here, we compare three genotyping techniques for their ability to reproduce the allele dosage of SNPs of interest in sugarcane (Saccharum spp.).
Hugo Jaimes +6 more
wiley +1 more source
Revista de Ciências da Saúde Nova Esperança, 2016 O metabolismo de fármacos visa transformá-lo em um intermediário com menor atividade e fácil de ser excretado. Dentre os diversos sistemas enzimáticos responsáveis por esse processo, destaca-se o citocromo P450. Este sistema oxidativo compreende 57 genes
Luciana Vilar Torres
doaj +1 more source
Revista Peruana de Medicina Experimental y Salud Pública, 2018 The aim of this study was to assess the relationship of the rs11191439 and rs3740393 polymorphisms of the Arsenite Methyltransferase (As3MT) gene with the arsenic urinary excretion profiles in a population in northern Mexico.
Francisco Javier García-Alvarado +3 more
doaj +1 more source
Estudios genéticos del metabolismo de la warfarina y su utilidad en la toma de decisiones
Revista Colombiana de Cardiología, 2022 Introducción: Al momento de valorar la necesidad de realizar un reemplazo quirúrgico valvular cardiaco es posible elegir entre una válvula mecánica o una bioprotésica; la elección debe tener presentes los riesgos de la terapia anticoagulante y la ...
Cristhian F. Ramírez-Ramos +4 more
doaj +1 more source