Results 21 to 30 of about 110,003 (222)

Achieving high immunogenicity against poliovirus with fractional doses of inactivated poliovirus vaccine in Ecuador-results from a cross-sectional serological survey

open access: yesThe Lancet Regional Health. Americas, 2022
Summary: Background: In January 2018, Ecuador changed its routine immunization schedule by replacing one full dose of inactivated poliovirus vaccine (IPV) administered intramuscularly at 2 months of age with two doses of fractional IPV (1/5th of full ...
Gabriel Trueba   +15 more
doaj   +1 more source

Feasibility of conducting intradermal vaccination campaign with inactivated poliovirus vaccine using Tropis intradermal needle free injection system, Karachi, Pakistan

open access: yesHeliyon, 2017
Background: Administration of intradermal fractional dose of inactivated poliovirus vaccine (fIPV) has proven to be safe and immunogenic; however, its intradermal application using needle and syringe is technically difficult and requires trained ...
Mohammad Tahir Yousafzai   +5 more
doaj   +1 more source

The human qualities needed to complete the global eradication of polio

open access: yesBulletin of the World Health Organization, 2013
Although the 99% decrease seen in global polio incidence between 1988 and 2000 represented remarkable progress towards polio eradication, tackling the last 1% of polio has proved tantalizingly difficult.
Dermot Maher
doaj   +1 more source

WHO Polio Eradication Program: Problems and Solutions

open access: yesПедиатрическая фармакология, 2016
In 2013 WHO re-evaluated its main goals of the polio eradication program. A modernization program was accepted with regard to the National vaccination calendars worldwide which includes a step-by-step refusal from the living polio vaccine (OPV) and a ...
S. M. Kharit   +3 more
doaj   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money   +5 more
wiley   +1 more source

Harnessing laboratory data for poliovirus eradication: contributions of the Africa regional polio laboratory data management team, 2022 – 2024

open access: yesComputer Methods and Programs in Biomedicine Update
Background and Objectives: Polio laboratory data is crucial in providing timely and accurate information on poliovirus outbreaks and therefore an important component of the overall poliovirus eradication strategies. This paper discusses the contributions
Brook Tesfaye   +14 more
doaj   +1 more source

Enterovirus infections in children

open access: yesPediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen   +11 more
wiley   +1 more source

Polio transition in the African Region: progress, challenges and prospects for health systems integration

open access: yesBMC Infectious Diseases
Background The Global Polio Eradication Initiative (GPEI) has made substantial progress towards global eradication of polio. As regions, including Africa, approach the final stages of this goal, countries must ensure that essential polio functions are ...
Terna Nomhwange   +10 more
doaj   +1 more source

Assessment of poliovirus antibody seroprevalence in high risk areas for vaccine derived poliovirus transmission in Madagascar

open access: yesHeliyon, 2018
Background: Vaccine-derived polioviruses (VDPV) outbreaks typically occur in areas of low poliovirus immunity. Madagascar successfully eradicated wild poliovirus in 1997; however, multiple VDPV outbreaks have occurred since then, and numerous vaccination
Richter Razafindratsimandresy   +6 more
doaj   +1 more source

Dream of Polio Free Pakistan - when will it become a reality?

open access: yesGlobal Biosecurity, 2023
Pakistan is one of the two endemic countries for polio, reporting co-circulation of WPV1 and cVDPV2. Pakistan is classified by the International Health Regulations (IHR) as a state infected with Wild Poliovirus type 1 (WPV1) and circulating Vaccine ...
Reetika Yadav   +3 more
doaj   +1 more source

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