Results 1 to 10 of about 2,052 (162)

Post-Polio Syndrome Revisited [PDF]

Neurology International, 2023
Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis.
Michael Punsoni, Nelli S. Lakis, Michelle Mellion, Suzanne M. de la Monte   +3 more
doaj   +4 more sources

Sensory Dysfunction in ALS and Other Motor Neuron Diseases: Clinical Relevance, Histopathology, Neurophysiology, and Insights from Neuroimaging [PDF]

Biomedicines
Background: The clinical profiles of MNDs are dominated by inexorable motor decline, but subclinical proprioceptive, nociceptive and somatosensory deficits may also exacerbate mobility, dexterity, and bulbar function.
Jana Kleinerova, Rangariroyashe H. Chipika, Ee Ling Tan, Yana Yunusova, Véronique Marchand-Pauvert, Jan Kassubek, Pierre-Francois Pradat, Peter Bede   +7 more
doaj   +2 more sources

West Nile neuroinvasive disease with poliomyelitis syndrome: A grave phenomenon [PDF]

SAGE Open Medical Case Reports
West Nile virus infection poses a significant threat, especially during the warmer months when mosquitoes are abundant. Clinicians must remain vigilant for neuroinvasive illness in patients presenting with febrile symptoms and malaise following mosquito ...
Benjamin Easow, Muhammad Qureshi, Saikiran Mandyam, Stephen Lavanier, Sanjida Jahan, Taylor Delie, Kateryna Feldman, Fnu Anshul   +7 more
doaj   +2 more sources

Differential diagnosis between post-polio syndrome symptoms and temporomandibular disorder – Clinical case [PDF]

Brazilian Journal of Oral Sciences, 2015
Post-poliomyelitis syndrome (PPS) is characterized by the delayed appearance of new neuromuscular symptoms in patients several years after their acute poliomyelitis paralysis.
Gustavo Augusto Seabra Barbosa, Maria Helena de Siqueira Torres Morais   +1 more
doaj   +2 more sources

Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities. [PDF]

Eur J Neurol
ABSTRACT Background There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While the MND/ALS literature is dominated by innovative brain studies, motor disability in ALS is primarily driven by neurogenic ...
Toomey A, Kleinerova J, Tan EL, Siah WF, Bede P.   +4 more
europepmc   +2 more sources

Guillain-Barré Syndrome Following Falciparum Malaria in an 18-Year Male Adolescent: A Rare Case Report and Literature Review. [PDF]

Clin Case Rep
ABSTRACT Guillain‐Barré Syndrome (GBS) is an immune‐mediated disorder affecting the peripheral nerves and nerve roots, potentially leading to severe complications such as respiratory failure and autonomic dysfunction. It is commonly preceded by gastrointestinal or respiratory infections, with various bacterial and viral pathogens identified as ...
Getahun GA, Arega G, Jemal MK, Woldie BG, Gudina EK.   +4 more
europepmc   +2 more sources

A Case of Miller-Fisher Overlap Syndrome With Positive Anti-GM4 Antibody and Atypical Symptoms. [PDF]

Immun Inflamm Dis
ABSTRACT Background Miller−Fisher syndrome (MFS) is a recognized clinical variant of Guillain−Barré syndrome (GBS), characterized by the classic triad of ophthalmoplegia, ataxia, and areflexia. When accompanied by additional symptoms such as bulbar palsy, limb weakness, or lethargy, it is termed MFS overlap syndrome.
Tang M, Tang R, Xu J, Yang Z, Zhang B, Yan Y, Xie J, Long Q, Li Z, Tu E.   +9 more
europepmc   +2 more sources

Frontotemporal Pathology in Motor Neuron Disease Phenotypes: Insights From Neuroimaging

Frontiers in Neurology, 2021
Frontotemporal involvement has been extensively investigated in amyotrophic lateral sclerosis (ALS) but remains relatively poorly characterized in other motor neuron disease (MND) phenotypes such as primary lateral sclerosis (PLS), progressive muscular ...
Mary Clare McKenna, Philippe Corcia, Philippe Corcia, Philippe Corcia, Philippe Couratier, Philippe Couratier, We Fong Siah, Pierre-Francois Pradat, Peter Bede, Peter Bede   +9 more
doaj   +1 more source

European Academy of Neurology/Peripheral Nerve Society Guideline on diagnosis and treatment of Guillain–Barré syndrome

European Journal of Neurology, Volume 30, Issue 12, Page 3646-3674, December 2023., 2023
Abstract Guillain–Barré syndrome (GBS) is an acute polyradiculoneuropathy. Symptoms may vary greatly in presentation and severity. Besides weakness and sensory disturbances, patients may have cranial nerve involvement, respiratory insufficiency, autonomic dysfunction and pain.
Pieter A. van Doorn, Peter Y. K. Van den Bergh, Robert D. M. Hadden, Bert Avau, Patrik Vankrunkelsven, Shahram Attarian, Patricia H. Blomkwist‐Markens, David R. Cornblath, H. Stephan Goedee, Thomas Harbo, Bart C. Jacobs, Susumu Kusunoki, Helmar C. Lehmann, Richard A. Lewis, Michael P. Lunn, Eduardo Nobile‐Orazio, Luis Querol, Yusuf A. Rajabally, Thirugnanam Umapathi, Haluk A. Topaloglu, Hugh J. Willison   +20 more
wiley   +2 more sources

Peripherin: A Novel Early Diagnostic and Prognostic Plasmatic Biomarker in Amyotrophic Lateral Sclerosis. [PDF]

Eur J Neurol
Plasma peripherin (PRPH) levels are significantly elevated in patients with motor neuron diseases (MND), including ALS, compared to both MND mimics and healthy controls. Higher baseline PRPH correlates with better functional status, slower disease progression, and longer survival, suggesting it may reflect an endogenous motor neuron injury response ...
Bombaci A, De Marco G, Casale F, Salamone P, Marchese G, Fuda G, Calvo A, Chiò A.   +7 more
europepmc   +2 more sources