Results 11 to 20 of about 2,050 (162)

Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities. [PDF]

Eur J Neurol
ABSTRACT Background There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While the MND/ALS literature is dominated by innovative brain studies, motor disability in ALS is primarily driven by neurogenic ...
Toomey A, Kleinerova J, Tan EL, Siah WF, Bede P.   +4 more
europepmc   +2 more sources

Guillain-Barré Syndrome Following Falciparum Malaria in an 18-Year Male Adolescent: A Rare Case Report and Literature Review. [PDF]

Clin Case Rep
ABSTRACT Guillain‐Barré Syndrome (GBS) is an immune‐mediated disorder affecting the peripheral nerves and nerve roots, potentially leading to severe complications such as respiratory failure and autonomic dysfunction. It is commonly preceded by gastrointestinal or respiratory infections, with various bacterial and viral pathogens identified as ...
Getahun GA, Arega G, Jemal MK, Woldie BG, Gudina EK.   +4 more
europepmc   +2 more sources

A Case of Miller-Fisher Overlap Syndrome With Positive Anti-GM4 Antibody and Atypical Symptoms. [PDF]

Immun Inflamm Dis
ABSTRACT Background Miller−Fisher syndrome (MFS) is a recognized clinical variant of Guillain−Barré syndrome (GBS), characterized by the classic triad of ophthalmoplegia, ataxia, and areflexia. When accompanied by additional symptoms such as bulbar palsy, limb weakness, or lethargy, it is termed MFS overlap syndrome.
Tang M, Tang R, Xu J, Yang Z, Zhang B, Yan Y, Xie J, Long Q, Li Z, Tu E.   +9 more
europepmc   +2 more sources

European Academy of Neurology/Peripheral Nerve Society Guideline on diagnosis and treatment of Guillain–Barré syndrome

European Journal of Neurology, Volume 30, Issue 12, Page 3646-3674, December 2023., 2023
Abstract Guillain–Barré syndrome (GBS) is an acute polyradiculoneuropathy. Symptoms may vary greatly in presentation and severity. Besides weakness and sensory disturbances, patients may have cranial nerve involvement, respiratory insufficiency, autonomic dysfunction and pain.
Pieter A. van Doorn, Peter Y. K. Van den Bergh, Robert D. M. Hadden, Bert Avau, Patrik Vankrunkelsven, Shahram Attarian, Patricia H. Blomkwist‐Markens, David R. Cornblath, H. Stephan Goedee, Thomas Harbo, Bart C. Jacobs, Susumu Kusunoki, Helmar C. Lehmann, Richard A. Lewis, Michael P. Lunn, Eduardo Nobile‐Orazio, Luis Querol, Yusuf A. Rajabally, Thirugnanam Umapathi, Haluk A. Topaloglu, Hugh J. Willison   +20 more
wiley   +2 more sources

Peripherin: A Novel Early Diagnostic and Prognostic Plasmatic Biomarker in Amyotrophic Lateral Sclerosis. [PDF]

Eur J Neurol
Plasma peripherin (PRPH) levels are significantly elevated in patients with motor neuron diseases (MND), including ALS, compared to both MND mimics and healthy controls. Higher baseline PRPH correlates with better functional status, slower disease progression, and longer survival, suggesting it may reflect an endogenous motor neuron injury response ...
Bombaci A, De Marco G, Casale F, Salamone P, Marchese G, Fuda G, Calvo A, Chiò A.   +7 more
europepmc   +2 more sources

Anterior Opening‐Wedge High Tibial Osteotomy in the Setting of Genu Recurvatum

Arthroscopy Techniques, Volume 12, Issue 11, Page e1859-e1866, November 2023., 2023
Abstract Patients with pathologic genu recurvatum may present with complaints regarding anterior knee pain, instability, loss of range of motion, or locking episodes of the knee. Symptomatic genu recurvatum refractory to conservative measures may require surgical treatment.
Harkirat Jawanda, Christopher M. Brusalis, Sachin Allahabadi, Benjamin Kerzner, Daniel J. Kaplan, Felicitas Allende, Obianuju A. Obioha, Zeeshan A. Khan, Robert F. LaPrade, Jorge Chahla   +9 more
wiley   +1 more source

Applying the polio model to New Zealand: The contingent role of socioeconomic status in infectious disease mortality

American Journal of Biological Anthropology, Volume 180, Issue 3, Page 561-572, March 2023., 2023
Abstract Objectives The traditional polio model depicts a positive relationship between the disease and socioeconomic status (SES), with higher SES associated with exposure to the poliovirus beyond infancy/early childhood and a higher mortality rate. This study uses occupation data from non‐Māori New Zealand death registrations and the Census to assess
Heather T. Battles
wiley   +1 more source

Guillain–Barre Syndrome following lower segment caesarean section under spinal anesthesia: A case report

Clinical Case Reports, Volume 10, Issue 10, October 2022., 2022
Abstract Symptoms of Guillain–Barre Syndrome (GBS) may be mistaken for typical puerperal changes, delaying diagnosis. Surgery and anesthesia may be triggers for GBS with an overall increase in pro‐inflammatory cytokines in the postpartum period. We report a unique case of GBS in the postpartum period who made a good recovery with supportive measures.
Prajjwol Luitel, Devansh Upadhyay, Nischal Neupane, Sujan Paudel, Prashant Gyawali, Bikram Prasad Gajurel, Ragesh Karn, Reema Rajbhandari, Niraj Gautam, Ashish Shrestha, Rajeev Ojha   +10 more
wiley   +1 more source

Neurological outcomes 1 year after COVID‐19 diagnosis: A prospective longitudinal cohort study

European Journal of Neurology, Volume 29, Issue 6, Page 1685-1696, June 2022., 2022
Out of 81 patients, 48 (59%) reported persistent symptoms that were not evident before COVID‐19 at the 1‐year follow‐up. New and persistent neurological disorders were found in 15% (3 months) and 12% (10/81; 1‐year). Cognitive deficits one year after COVID‐19 were apparent in 18%, whereas depression, anxiety, and post‐traumatic stress disorders were ...
Verena Rass, Ronny Beer, Alois Josef Schiefecker, Anna Lindner, Mario Kofler, Bogdan Andrei Ianosi, Philipp Mahlknecht, Beatrice Heim, Marina Peball, Federico Carbone, Victoria Limmert, Philipp Kindl, Lauma Putnina, Elena Fava, Sabina Sahanic, Thomas Sonnweber, Wolfgang N. Löscher, Julia V. Wanschitz, Laura Zamarian, Atbin Djamshidian, Ivan Tancevski, Günter Weiss, Rosa Bellmann‐Weiler, Stefan Kiechl, Klaus Seppi, Judith Loeffler‐Ragg, Bettina Pfausler, Raimund Helbok   +27 more
wiley   +1 more source

Amyotrophic lateral sclerosis represents corticomotoneuronal system failure. [PDF]

Muscle Nerve
Abstract Several decades have passed since the anterograde corticomotoneuronal hypothesis for amyotrophic lateral sclerosis (ALS) was proposed. The intervening years have witnessed its emergent support based on anatomical, pathological, physiological, neuroimaging, and molecular biological studies.
Eisen A, Vucic S, Kiernan MC.
europepmc   +2 more sources