Results 81 to 90 of about 103,271 (249)

Estimands for Early‐Phase Dose Optimization Trials in Oncology

open access: yesBiometrical Journal, Volume 67, Issue 5, October 2025.
ABSTRACT Phase I dose escalation trials in oncology generally aim to find the maximum tolerated dose. However, with the advent of molecular‐targeted therapies and antibody drug conjugates, dose‐limiting toxicities are less frequently observed, giving rise to the concept of optimal biological dose (OBD), which considers both efficacy and toxicity.
Ayon Mukherjee   +2 more
wiley   +1 more source

Pediatrics Poliomyelitis

open access: yesAktualʹnaâ Infektologiâ, 2016
The paper deals with the problems of diagnosis, differentiated diagnosis, dispensary for disease, prevention and treatment of poliomyelitis in children. There are presented the WHO guidelines on poliomyelitis for Ukraine.
O.K. Koloskova   +2 more
doaj   +1 more source

The physiological cost index of walking with a powered knee ankle foot orthosis in subjects with poliomyelitis : A pilot study [PDF]

open access: yes, 2015
Background: A powered knee ankle foot orthosis (KAFO) was developed to provide restriction of knee flexion during stance phase and active flexion and extension of the knee during swing phase of gait.
Allard P   +18 more
core   +1 more source

Socioeconomic determinants of vaccination against pneumococcus in 763 945 patients with heart failure

open access: yesESC Heart Failure, Volume 12, Issue 5, Page 3750-3754, October 2025.
Respiratory infections heighten risks for heart failure (HF) patients, yet 2020 data from France show low vaccination rates: 12.6% for pneumococcus and 63.1% for influenza. Using logistic regression on 763,945 HF patients, older age, female sex, and social deprivation were associated with lower pneumococcus vaccination, despite frequent healthcare ...
F. Roubille   +6 more
wiley   +1 more source

Vaccineassociated paralytic poliomyelitis and acute flaccid paralysis on some territories of Russia during 20 years

open access: yesЖурнал инфектологии, 2019
Aim: Analysis of the morbidity of vaccine-associated paralytic poliomyelitis and acute flaccid paralysis and the results of virological investigation of the patients on 14 territories of the Russian Federation in 1998-2017.
N. I. Romanenkova   +4 more
doaj   +1 more source

Zika virus infection in the returning traveller: what every neurologist should know [PDF]

open access: yes, 2018
Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers ...
Brito Ferreira, Maria Lucia   +6 more
core   +6 more sources

A Case of Miller−Fisher Overlap Syndrome With Positive Anti‐GM4 Antibody and Atypical Symptoms

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 10, October 2025.
ABSTRACT Background Miller−Fisher syndrome (MFS) is a recognized clinical variant of Guillain−Barré syndrome (GBS), characterized by the classic triad of ophthalmoplegia, ataxia, and areflexia. When accompanied by additional symptoms such as bulbar palsy, limb weakness, or lethargy, it is termed MFS overlap syndrome.
Miao Tang   +9 more
wiley   +1 more source

Wallerian Degeneration Surveyed in Poliomyelitis [PDF]

open access: yes, 2017
Poliomyelitis is a highly infectious disease rendering varying degrees of respiratory illness, gastroenteritis, malaise and potentially severe forms of paralysis. Infection is generated by a virus belonging in the Picornaviridae family.
Kelliher, Kevin R.   +4 more
core  

IMMUNOPROPHYLAXY OF POLYOMYELITIS: FROM THE FIRST INACTIVE TO THE LAST PERORAL VACCINE, OR HOW CLOSE IS THE «END OF THE GAME»?

open access: yesМедицинский совет, 2018
Vaccination is the most important tool for combating infectious diseases. There are a number of major vaccine-preventable diseases included in the national calendar of preventive vaccinations Russian Federation (latest revision is regulated by Decree of ...
O. A. Rychkova, M. A. Grakhova
doaj   +1 more source

Portugal e a Europa livres da poliomielite.

open access: yesActa Médica Portuguesa, 2003
On the 21st of June 2002, in Copenhagen, the Regional Commission for the Certification of Poliomyelitis Eradication, declared the European Region of the World Health Organization (WHO) as polio-free.
Guilherme Gonçalves   +4 more
doaj   +1 more source

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