Results 11 to 20 of about 1,716,389 (207)

Effect of Inactivated Poliovirus Vaccine Campaigns, Pakistan, 2014–2017

Emerging Infectious Diseases, 2018
Pakistan began using inactivated poliovirus vaccine alongside oral vaccine in mass campaigns to accelerate eradication of wild-type poliovirus in 2014.
Nicholas C. Grassly, Mufti Zubair Wadood, Rana M. Safdar, Abdirahman Sheikh Mahamud, Roland W. Sutter   +4 more
doaj   +2 more sources

Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine

Human Vaccines & Immunotherapeutics, 2021
The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao, Jing Li, Hongyuan Shi, Hui Ye, Rufei Ma, Yuting Fu, Xiaochang Liu, Guoliang Li, Xiaolei Yang, Zhimei Zhao, Jingsi Yang   +10 more
doaj   +2 more sources

Lessons from Vaccine-Related Poliovirus in Israel, UK and USA

Vaccines, 2022
Genetic variants of vaccine poliovirus type 2, imported from an unknown source, were detected in waste waters in Jerusalem, London and New York in early 2022.
T. Jacob John, Dhanya Dharmapalan
doaj   +2 more sources

Vaccine-related poliovirus shedding in trivalent polio vaccine and human immunodeficiency virus status: analysis from under five children

BMC Research Notes, 2017
Background Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal–oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein.
Joanne Hassan, Laura Wangai, Peter Borus, Christopher Khayeka–Wandabwa, Lucy Wanja Karani, Mercy Kithinji, Michael Kiptoo   +6 more
doaj   +2 more sources

Immunogenicity and safety of novel oral polio vaccine type 2 (nOPV2) in pediatric populations: a systematic review and Bayesian meta-analysis [PDF]

BMC Infectious Diseases
Background Following the 2016 global cessation of oral poliovirus vaccine type 2, outbreaks of circulating vaccine-derived poliovirus type 2 have posed significant public health challenges.
José Luís Boene, Letícia Rocha Campos, Gisella Chiara Carpi, Monica Muhawenimana, Sandra Helena Machado, Nilsa de Deus, Adilson Fernando Loforte Bauhofer   +6 more
doaj   +2 more sources

Comparative Randomized Study of Tolerability, Reactogenicity, Immunogenicity and Safety of the Vaccine «BiVac Polio» (Oral Poliovirus Vaccine Type 1,3) [PDF]

Эпидемиология и вакцинопрофилактика, 2017
Through the use of trivalent oral poliovirus vaccine made from Sabin strains of types 1, 2, 3 (tOPV), outstanding success of Global polio eradication program has been achieved. Since 1999, wild polio virus type 2 does not circulate in the world.
Yu. H. Khapchaev, O. E. Ivanova, M. F. Vorovitch, V. V. Romanenko, A. E. Makarov, S. G. Drozdov, A. A. Ishmukhametov   +6 more
doaj   +2 more sources

Novel Oral Poliovirus Vaccine 2 Safety Evaluation during Nationwide Supplemental Immunization Activity, Uganda, 2022

Emerging Infectious Diseases
Given its enhanced genetic stability, novel oral poliovirus vaccine type 2 was deployed for type 2 poliovirus outbreak responses under World Health Organization Emergency Use Listing. We evaluated the safety profile of this vaccine.
Farrell A. Tobolowsky, Fred Nsubuga, Zunera Gilani, Annet Kisakye, Helen Ndagije, Daniel Kyabayinze, Jane F. Gidudu   +6 more
doaj   +2 more sources

Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]

Vaccines
Poliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han, Jinbo Xiao, Shiyao Zhang, Tongyue Su, Yinuo Liu, Yong Zhang   +5 more
doaj   +2 more sources

Development and Validation of a Quantitative RT-qPCR Panel for the Detection and Monitoring of Polioviruses in Wastewater Samples [PDF]

Microorganisms
Clusters of acute flaccid paralysis (AFP) caused by oral vaccine-derived poliovirus (VDPV) in 2022 and sporadic outbreaks in New York and Gaza highlight the ongoing risk of polio, alongside the persistent global threat posed by wild-type poliovirus. This
Linnet Immaraj, Judy Y. Qiu, Logan A. Brand, Tiejun Gao, Bonita Lee, Michael Parkins, Casey Hubert, Christine O’Grady, Xiaoli Pang   +8 more
doaj   +2 more sources

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden [PDF]

BMJ Global Health, 2019
Background Our understanding of the acquisition of intestinal mucosal immunity and the control of poliovirus replication and transmission in later life is still emerging.Methods As part of a 2011 randomised, blinded, placebo-controlled clinical trial of ...
Elizabeth B Brickley, Ruth I Connor, Wendy F Wieland-Alter, Marc S Collett, Marianne Hartford, Harrie Van Der Avoort, Austin W Boesch, Joshua A Weiner, Margaret E Ackerman, Mark A McKinlay, Minetaro Arita, Ananda S Bandyopadhyay, John F Modlin, Peter F Wright   +13 more
doaj   +2 more sources