Results 61 to 70 of about 15,408 (221)

Trends and measurement of HIV prevalence in northern Malawi.

, 2003
BACKGROUND: Most data on HIV prevalence in Malawi come from antenatal clinic (ANC) surveillance and are, therefore, subject to bias. OBJECTIVES: HIV prevalence and risk factors were measured using population-based data to assess the accuracy of ANC ...
Crampin, Amelia C, Fine, Paul E, Glynn, Judith R, Mwaungulu, Frank D, Ngwira, Bagrey M, Pönnighaus, Jörg M, Warndorff, David K   +6 more
core   +1 more source

Comparative study of antibody levels developed by vaccination against polio virus in population after vaccine type alteration [PDF]

, 2015
During clinical trials, samples from Hungarian patients of different age groups were tested for antibodies against all 3 serotypes of poliovirus, a member of Picornaviridae family.
Farkas, Ágnes, Magyar, Nóra, Szomor, Katalin, Takács, Mária   +3 more
core   +1 more source

Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine

Cancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Glioblastoma (GBM) is an aggressive primary brain tumor with poor prognosis and low survival rates. Standard treatments, such as surgery and radiotherapy, are limited by tumor infiltration and resistance. To review current vaccine strategies for GBM, including peptide, virotherapy, cell‐based, and genetic vaccines, with a focus on ...
Sama Barati, Sahar Ghoflchi, Pejman Hosseinzadeh, Sobhan Pouramini, Hossein Hosseini, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

From regional pulse vaccination to global disease eradication: insights from a mathematical model of Poliomyelitis [PDF]

, 2014
Mass-vaccination campaigns are an important strategy in the global fight against poliomyelitis and measles. The large-scale logistics required for these mass immunisation campaigns magnifies the need for research into the effectiveness and optimal ...
AJ Terry, AL Lloyd, B Alyward, B Shulgin, Cameron J. Browne, CC Chicone, CJ Browne, DD Bainov, DD Bainov, DD Bainov, DJD Earn, DM Morens, HR Thieme, J Burton, J Liu, JM Heffernan, KR Yameogo, L Bourouiba, LS Liebovitch, Lydia Bourouiba, M Kirkilionis, ME Birmingham, N Bacaer, N Bacaer, N Bacaër, P Driessche van den, PEM Fine, R Breban, Robert J. Smith, S Zipursky, V Lakshmikantham, W Wang, X Meng, X-Q Zhao, Y Xiao, YP Yang, Z Agur   +36 more
core   +2 more sources

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Role of Serial Polio Seroprevalence Studies in Guiding Implementation of the Polio Eradication Initiative in Kano, Nigeria: 2011-2014. [PDF]

, 2016
BACKGROUND: Nigeria was one of 3 polio-endemic countries before it was de-listed in September 2015 by the World Health Organization, following interruption of transmission of the poliovirus. During 2011-2014, Nigeria conducted serial polio seroprevalence
Abdullahi Walla, Ado J. G. Muhammad, Amina Ahmad-Shehu, Bashir Abba, Centers for Disease Control and Prevention, Harish Verma, Kebba Touray, Kehinde TemilolaOluwa Craig, Marina Takane, Olen, Pascal Mkanda, Peter Nsubuga, Richard Banda, Roland W. Sutter, Rui G. Vaz, Sisay G. Tegegne, Ticha Johnson, World Health Organization, Yared G. Yehualashet, Zubairu Iliyasu   +19 more
core   +1 more source

Natural Killer Cell‐Mediated Antitumor Immunity: Molecular Mechanisms and Clinical Applications

MedComm, Volume 6, Issue 9, September 2025.
NK cells eliminate tumors via cytotoxicity and cytokine secretion. Tumor microenvironment‐driven immunosuppression and metabolic reprogramming subvert NK cells’ cytotoxicity. The current clinical strategies to restore NK activity include ex vivo expansion for adoptive transfer, CAR‐NK engineering, TME‐remodeling agents, immune checkpoint blockade ...
Nanzhi Luo, Cong Chen, Wenjing Zhou, Jianqi Hao, Song He, Yu Liu, Yin Ku, Linhua Huang, Chuanfen Zhang, Yueli Shu, Xiaoqing Wu, Yaojia Zhou, Jian Zhang   +12 more
wiley   +1 more source

Polio control after certification: major issues outstanding

Bulletin of the World Health Organization, 2004
Now that the global eradication of wild poliovirus is almost within sight, planning for the post-certification era is becoming a priority issue. It is agreed that a stockpile of appropriate polio vaccines will need to be established, and a surveillance ...
Fine Paul E.M., Oblapenko George, Sutter Roland W.   +2 more
doaj  

Twenty-Eight Years of Poliovirus Replication in an Immunodeficient Individual: Impact on the Global Polio Eradication Initiative.

PLoS Pathogens, 2015
There are currently huge efforts by the World Health Organization and partners to complete global polio eradication. With the significant decline in poliomyelitis cases due to wild poliovirus in recent years, rare cases related to the use of live ...
Glynis Dunn, Dimitra Klapsa, Thomas Wilton, Lindsay Stone, Philip D Minor, Javier Martin   +5 more
doaj   +1 more source

Effect of human rotavirus vaccine on severe diarrhea in African infants [PDF]

, 2016
BACKGROUND: Rotavirus is the most common cause of severe gastroenteritis among young children worldwide. Data are needed to assess the efficacy of the rotavirus vaccine in African children.
Cheuvart, BB, Cunliffe, NA, Gillard, PH, Han, HH, Kirsten, M, Louw, C, Madhi, SA, Neuzil, KM, Ngwira, B, Steele, D, Victor, JC, Witte, D   +11 more
core   +1 more source