Results 81 to 90 of about 9,051 (207)
Background: After stopping serotype 2–containing oral poliovirus vaccine use, serotype 2 poliovirus outbreaks may still occur and require outbreak response supplemental immunization activities (oSIAs).
Kimberly M. Thompson ScD +3 more
core +1 more source
Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]
The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Parker, EP +14 more
core +1 more source
According to manufacturers, inactivated poliovirus vaccines (IPVs) are freeze sensitive and require storage between 2\ub0C and 8\ub0C, whereas oral poliovirus vaccine requires storage at -20\u202f\ub0C.
core
Background: In 2016, the Global Polio Eradication Initiative (GPEI) recommended the cessation of using type 2 oral poliovirus vaccine (OPV) and OPV, with countries having to switch from the trivalent to bivalent OPV (bOPV) with the addition of ...
T. Jacob John +5 more
core +1 more source
Circulating vaccine-derived polioviruses: current state of knowledge
Within the past 4 years, poliomyelitis outbreaks associated with circulating vaccine-derived polioviruses (cVDPVs) have occurred in Hispaniola (2000-01), the Philippines (2001), and Madagascar (2001-02).
Kew Olen M. +6 more
doaj
Introduction: Prior research explores whether seasonal and childhood vaccines mitigate the risk of SARS-CoV-2 infection. Although there are trials investigating COVID-19 infection in response to the effects of the oral poliovirus vaccine (OPV), there has
Chisom Azodoh +6 more
core +1 more source
Boosting of Mucosal Immunity After Fractional-Dose Inactivated Poliovirus Vaccine
BACKGROUND. Inactivated poliovirus vaccine (IPV) boosts mucosal immunity in persons previously vaccinated with oral poliovirus vaccine (OPV). We assessed whether fractional-dose IPV (fIPV, 1/5th of full dose) administered intradermally also boosts ...
Yiting Zhang +15 more
core +1 more source
Preeradication Vaccine Policy Options for Poliovirus Infection and Disease Control
With the circulation of wild poliovirus (WPV) types 1 and 3 continuing more than a decade after the original goal of eradicating all three types of WPVs by 2000, policymakers consider many immunization options as they strive to stop transmission in the ...
Thompson, Kimberly M. +10 more
core +2 more sources
BackgroundThe "gold standard" for assessing mucosal immunity after vaccination with poliovirus vaccines consists in measuring virus excretion in stool after challenge with oral poliovirus vaccine (OPV).
Ayan Dey +12 more
doaj +1 more source
Background Oral polio vaccine (OPV) containing attenuated serotype 2 polioviruses was globally withdrawn in 2016, and bivalent OPV (bOPV) containing attenuated serotype 1 and 3 polioviruses needs to be withdrawn after the certification of eradication of ...
Lee M. Hampton +2 more
core +1 more source

