Results 61 to 70 of about 9,051 (207)

Sodium Copper Chlorophyllin Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection Through Multiple Antiviral Mechanisms

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to the global swine industry due to its extensive genetic diversity and limited vaccine cross‐protection. Antiviral strategies that target both viral infection and host pathological responses are urgently needed.
Xinrong Wang, Juan Zhang, Li Rui, Junhai Zhu, Nan Yan, Meiyu Jia, Longxiang Zhang, Lizhi Fu, Yue Wang, Jianchao Wei   +9 more
wiley   +1 more source

Polio control after certification: major issues outstanding

Bulletin of the World Health Organization, 2004
Now that the global eradication of wild poliovirus is almost within sight, planning for the post-certification era is becoming a priority issue. It is agreed that a stockpile of appropriate polio vaccines will need to be established, and a surveillance ...
Fine Paul E.M., Oblapenko George, Sutter Roland W.   +2 more
doaj  

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Determination of Factors Affecting Bivalent (Type 1 and 3) Stability of Oral Poliomyelitis Vaccine

Medical Laboratory Journal, 2020
Background and objectives: After using of trivalent oral poliovirus vaccine (OPV) for a long time in Iran, in recent years, due to the eradication of type 2 of poliovirus, a bivalent vaccine containing types 1 and 3 is used.
Sina Soleimani
doaj  

Twenty-Eight Years of Poliovirus Replication in an Immunodeficient Individual: Impact on the Global Polio Eradication Initiative.

PLoS Pathogens, 2015
There are currently huge efforts by the World Health Organization and partners to complete global polio eradication. With the significant decline in poliomyelitis cases due to wild poliovirus in recent years, rare cases related to the use of live ...
Glynis Dunn, Dimitra Klapsa, Thomas Wilton, Lindsay Stone, Philip D Minor, Javier Martin   +5 more
doaj   +1 more source

A Pseudovirus‐Based Method for the Simultaneous Quantitation of Neutralization Antibodies Against All Three Poliovirus Serotypes

MedComm, Volume 6, Issue 12, December 2025.
By optimizing P1 expression, sensitive cell selection, and plasmid transfection ratios, we produced a high‐titer poliovirus pseudovirus. Based on high‐titer pseudovirus encoding distinct fluorophores (E2, eGFP, and RFP), we developed a tri‐color pseudovirus‐based neutralization assay (PBNA) for the simultaneous quantification of neutralizing antibodies
Meiyan Liu, Yuanling Yu, Yadong Li, Zexin Tao, Lan Huang, Xi Wu, Yong Zhang, Shuangli Zhu, Qiang Sun, Tianjiao Ji, Dongyan Wang, Ziteng Liang, Shuo Liu, Meina Cai, Yimeng An, Jierui Li, Weijin Huang, Guoyang Liao, Li Yi, Lei Ma, Li Zhang, Youchun Wang   +21 more
wiley   +1 more source

Crosstalk Between Cancer‐Associated Fibroblasts and Immune Cells: Mechanisms and Therapeutic Implications

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Cancer‐associated fibroblasts (CAFs) are widely engaged in tumor progression in the tumor microenvironment. CAFs interact actively with immunocytes including tumor‐associated macrophages, T cells, neutrophils, and NK cells in a positive‐feedback loop to sculpt tumor immune microenvironment and participate in tumor activities and antitumor therapy ...
Ya Li, Xingpeng Di, Jiawei Chen, Jingwen Wei, Tianyue Li, Kunjie Wang, Banghua Liao, Deyi Luo   +7 more
wiley   +1 more source

Decay of Sabin inactivated poliovirus vaccine (IPV)-boosted poliovirus antibodies

, 2015
IntroductionWe conducted a follow-on study to a phase I randomized, controlled trial conducted in Cuba, 2012, to assess the persistence of poliovirus antibodies at 21–22months following booster dose of Sabin-IPV compared to Salk-IPV in adults who had ...
Fonseca, Magile, Sein, Carolyn, Resik, Sonia, Tejeda, Alina, Okayasu, Hiromasa, Sutter, Roland W., Hung, Lai Heng, Diaz, Manuel, Martinez, Yenisleidys   +8 more
core   +1 more source

The microbiome in cancer

iMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

Vaccine-Derived Poliovirus Infection among Patients with Primary Immunodeficiency and Effect of Patient Screening on Disease Outcomes, Iran

Emerging Infectious Diseases, 2019
Patients with immunodeficiency-associated vaccine-derived poliovirus (iVDPV) are potential poliovirus reservoirs in the posteradication era that might reintroduce polioviruses into the community.
Mohammadreza Shaghaghi, Shohreh Shahmahmoodi, Ali Nili, Hassan Abolhassani, Seyedeh Panid Madani, Ahmad Nejati, Maryam Yousefi, Yaghoob M. Kandelousi, Mona Irannejad, Shiva Shaghaghi, Seyed Mohsen Zahraei, Sussan Mahmoudi, Mohammad Mehdi Gouya, Reza Yazdani, Gholamreza Azizi, Nima Parvaneh, Asghar Aghamohammadi   +16 more
doaj   +1 more source