Results 61 to 70 of about 1,716,389 (207)

The evolving role of immunotherapy in ovarian cancer

Cancer, Volume 132, Issue 18, 15 September 2026.
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani, Laura Venegas, Amit M. Oza   +2 more
wiley   +1 more source

Vaccine [PDF]

In 2012, the Strategic Advisory Group of Experts on Immunization (SAGE) recommended introduction of at least one inactivated poliovirus vaccine (IPV) dose in essential immunization programs.

core   +4 more sources

Sabin polio virus protein 1 (VP1) evolution in patients with acute flaccid paralysis from 2010 to 2016 in Uganda

Virology Journal, 2023
Acute flaccid paralysis (AFP) is a rare side effect of the oral polio vaccine but can be associated with outbreaks and permanent disability in patients harboring circulating vaccine-derived polioviruses (cVDPVs).
Mary Bridget Nanteza, Barnabas Bakamutumaho, Phionah Tushabe, Prossy Namuwulya, Molly Birungi, Rajab Dhatemwa, James Peter Eliku, Mayi Tibanagwa, Proscovia Kakooza, Henry Bukenya, Josephine Bwogi, Charles Rutebarika Byabamazima   +11 more
doaj   +1 more source

Decay of Sabin inactivated poliovirus vaccine (IPV)-boosted poliovirus antibodies [PDF]

, 2015
IntroductionWe conducted a follow-on study to a phase I randomized, controlled trial conducted in Cuba, 2012, to assess the persistence of poliovirus antibodies at 21–22months following booster dose of Sabin-IPV compared to Salk-IPV in adults who had ...
Fonseca, Magile, Sein, Carolyn, Resik, Sonia, Tejeda, Alina, Okayasu, Hiromasa, Sutter, Roland W., Hung, Lai Heng, Diaz, Manuel, Martinez, Yenisleidys   +8 more
core   +1 more source

Pediatric case with vaccine-related poliovirus infection: A case report

, 2021
BACKGROUND As long as oral poliovirus vaccine (OPV) is used, the potential risk for the emergence of vaccine-related polioviruses remains. CASE SUMMARY We report a case of Sabin-like type 1 poliovirus infection in an immunocompetent 17-mo-old child after
Farshadpour, F, Taherkhani, R
core   +1 more source

Poliovirus shedding after sequential immunization of Sabin-strain inactivated polio vaccines and oral attenuated polio vaccines

npj Vaccines
The identification of poliovirus in stool samples post-Oral Poliovirus Vaccine (OPV) immunization is essential for implementing post-eradication monitoring of poliomyelitis.
Yuting Fu, Rufei Ma, Zhimei Zhao, Zhaojun Mo, Zhifang Ying, Jing Li, Hui Ye, Guoliang Li, Xiaochang Liu, Jiangli Liang, Ling Ping, Jingyan Li, Junhui Tao, Qinghai Yang, Dingkai Wei, Li Yi, Hongbo Chen, Jianfeng Wang, Ruiju Jiang, Lei Yu, Wei Cai, Wei Yang, Lei Yue, Mingxue Xie, Qiongzhou Yin, Jing Pu, Chao Hong, Lukui Cai, Yan Deng, Jiana Wen, Yan Ma, Na Gao, Xiaoyu Wang, Hongwei Liao, Qiuyan Ji, Guang Ji, Wenzhu Hu, Qin Gu, Xiaoyue He, Han Chu, Yixian Fu, Jian Zhou, Yu Wen, Xiaolei Yang, Changgui Li, Li Shi, Ting Zhao, Teng Huang, Jingsi Yang   +48 more
doaj   +1 more source

Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania

Journal of Paediatrics and Child Health, Volume 62, Issue 7, Page 1113-1120, July 2026.
ABSTRACT Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...
Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao   +17 more
wiley   +1 more source

An Unusual Case of Vaccine-Associated Paralytic Poliomyelitis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2014
The present article reports a case involving an immunocompetent, previously well child who, despite two previous doses of inactivated poliovirus vaccine, developed severe flaccid paralysis consistent with polio after receiving oral polio vaccine.
S Desai, T Diener, BJ-K Tan, NJ Lowry, C Talukdar, WM Chrusch, S Wiebe   +6 more
doaj   +1 more source

A Protocol of National Mixed‐Methods Assessment of Childhood and Maternal Immunization

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Accurate measurement of routine immunization coverage is essential for detecting immunity gaps, guiding programmatic responses, and supporting equitable vaccine delivery. Iran's Expanded Programme on Immunization has achieved high coverage, but administrative estimates can mask some disparities.
Seyed Aria Nejadghaderi, Paria Dehesh, Mehran Nakhaeizadeh, Mohammadreza Rajabalipour, Faeze Tahrudi, Naser Nasiri, Seyed Mohsen Zahraei, Hamid Sharifi, AliAkbar Haghdoost   +8 more
wiley   +1 more source

Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode, Mitchel C. Rothholz, Stephan L. Foster, Erica R. Brody, John D. Gräbenstein   +4 more
wiley   +1 more source