Results 101 to 110 of about 1,716,389 (207)

Advances and challenges in poliomyelitis vaccines: a comprehensive review of development, production, and global deployment

Frontiers in Public Health
Poliomyelitis has been a significant global health challenge for centuries. Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988, remarkable progress has been achieved, with wild poliovirus (WPV) cases reduced by over 99%.
Jia Liang, Qi Zhang, Yanan Li, Lili Wang
doaj   +1 more source

Viral Aetiology of Acute Flaccid Paralysis Surveillance Cases, before and after Vaccine Policy Change from Oral Polio Vaccine to Inactivated Polio Vaccine

Journal of Tropical Medicine, 2014
Since 1992, surveillance for acute flaccid paralysis (AFP) cases was introduced in Malaysia along with the establishment of the National Poliovirus Laboratory at the Institute for Medical Research.
T. S. Saraswathy Subramaniam, Mohd Apandi Apandi, Rohani Jahis, Mohd Samsul Samsudin, Zainah Saat   +4 more
doaj   +1 more source

Inactivated Poliovirus Vaccine Booster Reduces the Likelihood of COVID-19 Outcomes in Individuals Primed with Oral Poliovirus Vaccination

Introduction: Prior research explores whether seasonal and childhood vaccines mitigate the risk of SARS-CoV-2 infection. Although there are trials investigating COVID-19 infection in response to the effects of the oral poliovirus vaccine (OPV), there has
Chisom Azodoh, Lilly D. Engineer, Aditi Singh, Robin J. Larson, Yea-Jen Hsu, Erin Jackson-Ward, Brittany A. Comunale   +6 more
core   +1 more source

Boosting of Mucosal Immunity After Fractional-Dose Inactivated Poliovirus Vaccine

, 2018
BACKGROUND. Inactivated poliovirus vaccine (IPV) boosts mucosal immunity in persons previously vaccinated with oral poliovirus vaccine (OPV). We assessed whether fractional-dose IPV (fIPV, 1/5th of full dose) administered intradermally also boosts ...
Yiting Zhang, Gamage, Deepa, Ondrej Mach, Sutter, Roland W., Oberste, M. Steven, Weldon, William C., Zhang, Yiting, Gunasena, Sunethra, Mach, Ondrej, William C Weldon, Roland W Sutter, M Steven Oberste, Palihawadana, Paba, Deepa Gamage, Paba Palihawadana, Sunethra Gunasena   +15 more
core   +1 more source

Impediments to Progress Toward Polio Eradication During 2014–2024: Effectively Addressing the Current Challenges

Vaccines
When the Global Polio Eradication Initiative (GPEI) began in 1988, the year 2000 target was clearly ambitious. Nonetheless, among 20 countries with endemic wild poliovirus transmission in 2000, only Afghanistan, Nigeria and Pakistan remained endemic in ...
Steven G. F. Wassilak, Abdinoor Mohamed, John Paul Bigouette   +2 more
doaj   +1 more source

Planning for globally coordinated cessation of bivalent oral poliovirus vaccine: risks of non-synchronous cessation and unauthorized oral poliovirus vaccine use

, 2018
Background Oral polio vaccine (OPV) containing attenuated serotype 2 polioviruses was globally withdrawn in 2016, and bivalent OPV (bOPV) containing attenuated serotype 1 and 3 polioviruses needs to be withdrawn after the certification of eradication of ...
Lee M. Hampton, Kimberly M. Thompson, Radboud J. Duintjer Tebbens   +2 more
core   +1 more source

Novel Oral Polio Vaccine Type 2 Use for Polio Outbreak Response: A Global Effort for a Global Health Emergency

Pathogens
A sharp rise in circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks in the years following the cessation of routine use of poliovirus type 2-containing oral polio vaccine and the trend of seeding new emergences with suboptimal vaccination ...
Feyrouz Damji Kurji, Ananda Sankar Bandyopadhyay, Simona Zipursky, Laura V. Cooper, Chris Gast, Margaret Toher, Ralf Clemens, Sue Ann Costa Clemens, Rayasam Prasad, Adriansjah Azhari   +9 more
doaj   +1 more source

Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis.

, 2005
BACKGROUND: Decisions about the use of killed oral cholera vaccines, which confer moderate levels of direct protection to vaccinees, can depend on whether the vaccines also provide indirect (herd) protection when high levels of vaccine coverage are ...
Ali, Mohammad, Sack, David A., Emch, Michael, Holmgren, Jan, Holmgren, Jan,, Clemens, John D, Rao, Malla, von Seidlein, Lorenz, Yunus, Mohammad, Clemens, John D., Sack, David A   +10 more
core   +1 more source

Antiviral Development for the Polio Endgame: Current Progress and Future Directions

Pathogens
As the world is approaching the eradication of wild poliovirus serotype 1, the last of the three wild types, the question of how to maintain a polio-free world becomes imminent.
Hang Xie, Eric E. Rhoden, Hong-Mei Liu, Folake Ogunsemowo, Bernardo A. Mainou, Rachel M. Burke, Cara C. Burns   +6 more
doaj   +1 more source

The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern Malawi.

, 2005
BACKGROUND: The proportion of cases of tuberculosis due to recent infection can be estimated in long-term population-based studies using molecular techniques.
Yates, Malcolm D, Fine, Paul EM, Ngwira, Bagrey M., Traore, Hamidou, Crampin, Amelia C., Yates, Malcolm D., Fine, Paul E.M., Glynn, Judith R., Mwaungulu, Frank D., Glynn, Judith R, Mwaungulu, Frank D, Crampin, Amelia C, Drobniewski, Francis, Ndlovu, Richard, Ngwira, Bagrey M   +14 more
core   +1 more source