Results 91 to 100 of about 178,574,484 (267)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Pallidotomy – outdated procedure or modern therapeutic alternative? – a review

Journal of Education, Health and Sport
Introduction and purpose Pallidotomy is a neurosurgical procedure involving the ablation of the globus pallidus, resulting in reduced activity in this area of the brain.
Agnieszka Pociecha, Marta Kozikowska, Bożena Kmak   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The perception of facilitators and barriers to the use of e-health solutions in Poland: a qualitative study

BMC Medical Informatics and Decision Making
Background E-health entails the use of information and communication technologies in support of health and health-related activities. E-health increased significantly during the COVID-19 pandemic in Poland.
Paulina Smoła, Iwona Młoźniak, Monika Wojcieszko, Urszula Zwierczyk, Mateusz Kobryn, Elżbieta Rzepecka, Mariusz Duplaga   +6 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Medical Research Council of Ireland annual report for the year ended 31st December 1983

, 1983
The main remit of the Council is to promote and support medical research and this continues as in previous years, support taking the form of project grants and funding of special research units as well as the Council laboratories in Trinity College ...
Medical Research Council of Ireland
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CGIAR Collaborative Platform on Gender Research - Communities of Practice

, 2022
This presentation was given at the Annual Scientific Conference hosted by the CGIAR Collaborative Platform for Gender Research, Amsterdam, 5-6 December ...
CGIAR Collaborative Platform on Gender Research
core   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Medical Research Council of Ireland annual report for the year ended 31st December 1978

, 1978
The Medical Research Council. is primarily concerned with the excellence and veracity of investigative programmes. The role of medical research is one which is frequently raised by the lay person.
Medical Research Council of Ireland
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