Results 71 to 80 of about 11,399 (257)

Open Research Data at Gdańsk University of Technology – from project's assumptions to the integral part of scientific infrastructure

, 2021
One of the significant challenges for the academic environment-oriented to developing Open Science is Research Data Management (RDM) practices and infrastructures and their popularization among different stakeholders.
Szuflita-Żurawska, Magdalena, Wałek, Anna, Szczodruch, Robert   +2 more
core   +1 more source

Experiences of developing an educational course for librarians in international cooperation. MedLibTrain: a joint Polish-Norwegian project

, 2013
Medical librarians from Poland and Norway participated in the joint project MedLibTrain, and developed a training program for medical librarians performing teaching tasks.
Hunskår, Irene, Stenhammer, Anne Skjæret, Lein, Regina Küfner, Sletsjøe, Hege, Sieradzka-Fleituch, Malgorzata, Niedzwiedzka, Barbara, Stenhammer, Anne   +6 more
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

„Gong Głodomora” – humorystyczny obraz atmosfery intelektualnej i obyczajowości panującej w Zakładzie Przyrodoleczniczym doktora Apolinarego Tarnawskiego w Kosowie

Krakowskie Pismo Kresowe, 2018
Starveling’s Gong. A Humorous Portrayal of the Intellectual Atmosphere and Customs of the Natural Medicine Centre of Dr Apolinary Tarnawski in Kosow Starveling’s Gong is a unique copy of a satirical piece  in the form of a typewritten journal edited ...
Natalia Tarkowska
doaj   +1 more source

Transcriptional reprogramming by mutated IRF4 in lymphoma

Nature Communications, 2023
Disease-causing mutations in genes encoding transcription factors (TFs) can affect TF interactions with their cognate DNA-binding motifs. Whether and how TF mutations impact upon the binding to TF composite elements (CE) and the interaction with other ...
Nikolai Schleussner, Pierre Cauchy, Vedran Franke, Maciej Giefing, Oriol Fornes, Naveen Vankadari, Salam A. Assi, Mariantonia Costanza, Marc A. Weniger, Altuna Akalin, Ioannis Anagnostopoulos, Thomas Bukur, Marco G. Casarotto, Frederik Damm, Oliver Daumke, Benjamin Edginton-White, J. Christof M. Gebhardt, Michael Grau, Stephan Grunwald, Martin-Leo Hansmann, Sylvia Hartmann, Lionel Huber, Eva Kärgel, Simone Lusatis, Daniel Noerenberg, Nadine Obier, Ulrich Pannicke, Anja Fischer, Anja Reisser, Andreas Rosenwald, Klaus Schwarz, Srinivasan Sundararaj, Andre Weilemann, Wiebke Winkler, Wendan Xu, Georg Lenz, Klaus Rajewsky, Wyeth W. Wasserman, Peter N. Cockerill, Claus Scheidereit, Reiner Siebert, Ralf Küppers, Rudolf Grosschedl, Martin Janz, Constanze Bonifer, Stephan Mathas   +45 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology

Cell Reports, 2019
Summary: VPS10P domain receptors emerge as central regulators of intracellular protein sorting in neurons with relevance for various brain pathologies. Here, we identified a role for the family member SorCS2 in protection of neurons from oxidative stress
Anna R. Malik, Kinga Szydlowska, Karolina Nizinska, Antonino Asaro, Erwin A. van Vliet, Oliver Popp, Gunnar Dittmar, Raphaela Fritsche-Guenther, Jennifer A. Kirwan, Anders Nykjaer, Katarzyna Lukasiuk, Eleonora Aronica, Thomas E. Willnow   +12 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A collaborative resource platform for non-human primate neuroimaging [PDF]

, 2020
Neuroimaging non-human primates (NHPs) is a growing, yet highly specialized field of neuroscience. Resources that were primarily developed for human neuroimaging often need to be significantly adapted for use with NHPs or other animals, which has led to ...
Evrard, Henry C., Dadarwal, Rakshit, Giavasis, S., Sein, J., Garza-Villarreal, E.A., Evrard, H.C., Mars, Rogier,, Benn, R. Austin, Wang, Xindi, Glen, Daniel, Hartig, R., Mars, Rogier, B, Lepage, C., Milham, M., Tasserie, J., Sponheim, Caleb, Garcia-Saldivar, P., Garza-Villarreal, E., Hartig, Renée, Messinger, A., Mars, Rogier B., Benn, R Austin, Evrard, Henry C, Seidlitz, Jakob, Klink, P.C., Garza-Villarreal, Eduardo A, Jung, Benjamin, Milham, M.P., Seidlitz, J., Klink, P., Liu, Cirong, Rosa, Marcello GP, Mars, Rogier B, Evrard, H., Messinger, Adam, Liu, C., Rosa, Marcello G P, Heuer, Katja, Lepage, Claude, Rosa, M.G.P., Jung, B., Cagna, B., Klink, P Christiaan, Xu, T., Mars, R.B., Majka, Piotr, Margulies, Daniel S., Toro, R., Benn, R., Sponheim, C., Milham, Michael P, Loh, K., Taylor, P., Klink, P. Christiaan, Sirmpilatze, Nikoloz, Garcia-Saldivar, Pamela, Margulies, Daniel S, Dadarwal, R., Giavasis, Steven, Milham, Michael P., Margulies, D.S., Wang, X., Cagna, Bastien, Toro, Roberto, Benn, R.A., Glen, D., Heuer, K., Garza-Villarreal, Eduardo, Milham, Michael, Majka, P., Sein, Julien, Loh, Kep Kee, Tasserie, Jordy, Margulies, D., Uhrig, Lynn, Loh, K.K., Rosa, Marcello G.P., Mars, R., Sirmpilatze, N., Taylor, Paul, Evrard, Henry, Merchant, H., Uhrig, L., Merchant, Hugo, Garza-Villarreal, Eduardo A., Rosa, M., Xu, Ting, Margulies, Daniel   +87 more
core   +1 more source