Results 71 to 80 of about 220,770,914 (263)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Research Trainee Symposium: Molecular Medicine and Medical School Research Programs combined with the The Twenty-First Annual University of Utah Frank Tyler Fall Medical Student Research Symposium

, 2015
Official program and abstracts from the twenty-first annual Frank Tyler Fall Medical Student Research Symposium at the University of Utah.
Medical Student Research Program
core  

Irish Health Research Forum meeting. Theme: should Ireland set health research priorities? [PDF]

, 2018
This report presents the proceedings of the Irish Health Research Forum on May 21st, 2018 focusing on the topic of whether Ireland should set health research ...
Medical Research Charities Group
core  

Assessment of the effectiveness of medical simulators in the practical training of medical students: Preliminary results in MU-Varna [PDF]

, 2019
INTRODUCTION: Nowadays, simulators have become part of most medical universities’ educational strategy. In recent years, Medical University of Varna has been equipped with the most modern medical simulators, aiming to meet the practical training needs of
Chernogorova, Yanita; Medical University of Varna, Grancharov, Deyan; Medical University of Varna, Bliznakov, Zhivko; Medical University of Varna   +2 more
core   +7 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Research Trainee Symposium: Molecular Medicine and Medical School Research Programs combined with the The Twenty-Third Annual University of Utah Frank Tyler Fall Medical Student Research Symposium

, 2017
Official program and abstracts from the twenty-second annual Frank Tyler Fall Medical Student Research Symposium at the University of Utah.
Medical Student Research Program
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Medical Research Charities Group: Annual report 2016

, 2017
2016. Our role is to be the champion of medical research charities, enabling them to maximise their impact in all areas of health research and to highlight their incredibly important role in society.
Medical Research Charities Group
core  

TNF-α and IFN-s-Dependent Muscle Decay Is Linked to NF-κB- and STAT-1α-Stimulated Atrogin1 and MuRF1 Genes in C2C12 Myotubes

Mediators of Inflammation, 2013
TNF-α was shown to stimulate mitogenicity in C2C12 myoblasts. Selected cytokines TNF-α, IFNα, or IFNγ reduced the expression of myosin heavy chain (MyHC IIa) when given together.
Barbara Pijet, Maja Pijet, Anna Litwiniuk, Małgorzata Gajewska, Beata Pająk, Arkadiusz Orzechowski   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source