Results 51 to 60 of about 220,770,914 (263)
Transcriptional reprogramming by mutated IRF4 in lymphoma
Nature Communications, 2023 Disease-causing mutations in genes encoding transcription factors (TFs) can affect TF interactions with their cognate DNA-binding motifs. Whether and how TF mutations impact upon the binding to TF composite elements (CE) and the interaction with other ...
Nikolai Schleussner +45 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Medical Research Charities Group: Annual report 2018 [PDF]
, 2019 2018 was a year of high activity and much progress for the MRCG. Fourteen exciting research projects were funded through our Joint Funding Scheme with the HRB, two impactful Irish Health Research Forum events were held and we did much to support our ...
Medical Research Charities Group
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
CGIAR Collaborative Platform on Gender Research - Communities of Practice
, 2022 This presentation was given at the Annual Scientific Conference hosted by the CGIAR Collaborative Platform for Gender Research, Amsterdam, 5-6 December ...
CGIAR Collaborative Platform on Gender Research
core +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Medical Research Council of Ireland report for the year ended 31st December 1973 [PDF]
, 1973 Since it was established in 1937 the general funds of the Council, apart from the amount allocated to the Medical Research Council Laboratories, have gone almost entirely to the support of research in or associated with departments in medical schools ...
Medical Research Council of Ireland
core
Mapping the Future of Particle Radiobiology in Europe: The INSPIRE Project
Frontiers in Physics, 2020 Particle therapy is a growing cancer treatment modality worldwide. However, there still remains a number of unanswered questions considering differences in the biological response between particles and photons.
Nicholas T. Henthorn +43 more
doaj +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source