Results 61 to 70 of about 178,574,484 (267)

Recommendations on intellectual property and knowledge transfer for charity-funded research [PDF]

, 2018
A core belief of the HRCI is that charity-funded research should be used for public good; for the benefit of patients and to improve the nation’s health.
Medical Research Charities Group
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Research Trainee Symposium: Molecular Medicine and Medical School Research Programs combined with the The Twentieth Annual University of Utah Frank Tyler Fall Medical Student Research Symposium

, 2011
Official program and abstracts from the twentieth annual Frank Tyler Fall Medical Student Research Symposium at the University of Utah.
Medical Student Research Program
core  

Data protection and the health research regulations: finding a way forward: report and recommendations [PDF]

, 2019
This report presents the proceedings of the Irish Health Research Forum meeting on May 16th 2019 which focused on data protection and health research legislation, in the context of the Health Research ...
Medical Research Charities Group
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Research Trainee Symposium: Molecular Medicine and Medical School Research Programs combined with the The Twenty-Second Annual University of Utah Frank Tyler Fall Medical Student Research Symposium

, 2016
Official program and abstracts from the twenty-second annual Frank Tyler Fall Medical Student Research Symposium at the University of Utah.
Medical Student Research Program
core  

Safety and biodistribution of intrathecal administration of mesenchymal stem cells (MSCs) and neurotrophin-releasing nanoparticles in a porcine CSF-guided delivery model for amyotrophic lateral sclerosis (ALS) drug discovery

Scientific Reports
Amyotrophic lateral sclerosis (ALS) is a multifactorial neurodegenerative disorder that complicates the identification of effective therapeutic targets. The potential of stem cells and neurotrophins as promising candidates has become increasingly evident,
Emilia Sinderewicz, Maria Dąbkowska, Anna Sarnowska, Joanna Staszkiewicz-Chodor, Dorota Mystkowska, Piotr Holak, Igor Drozd, Magdalena Chodkowska-Michalowska, Monika Rytel, Edyta Paczkowska, Marcin P. Mycko, Boguslaw Machalinski, Katarzyna Jezierska-Wozniak   +12 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Research Trainee Symposium: Molecular Medicine and Medical School Research Programs combined with the The Twenty-Third Annual University of Utah Frank Tyler Fall Medical Student Research Symposium

, 2017
Official program and abstracts from the twenty-second annual Frank Tyler Fall Medical Student Research Symposium at the University of Utah.
Medical Student Research Program
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source