Results 41 to 50 of about 178,574,484 (267)

Activity and function of auxiliary fluxes of glucose metabolism in response to physiological normoxia (5 % O2) during long-term Adipose-Derived Stem/Stromal cell culture

European Journal of Cell Biology
Energy metabolism homeostasis emerges as a dominant element influencing mesenchymal stem/stromal cells’ trajectory of development. The predominant glycolysis activity is a primary driver of cell proliferation and maintenance of the high-energetic state ...
Paulina Rybkowska, Maria Kawalec, Dorota Dymkowska, Klaudia Radoszkiewicz, Barbara Zabłocka, Krzysztof Zabłocki, Anna Sarnowska   +6 more
doaj   +1 more source

Artificial meat? Feasible approach based on the experience from cell culture studies

Journal of Integrative Agriculture, 2015
This short review is to list pros and cons which are based on the literature and personal experience in cell culture studies related to possible commercial production of artificial meat as functional food.
Arkadiusz Orzechowski
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Examples of data modules on the Wroclaw Medical University Polish Platform of Medical Research - worked schemes and development plans = Przykłady modułów danych na Polskiej Platformie Medycznej Uniwersytetu Medycznego we Wrocławiu - wypracowane schematy oraz plany rozwojowe

Forum Bibliotek Medycznych, 2023
Polish Platform of Medical Research (PPM) is a knowledge and research potential management platform for Polish academic institutions from the medical field which participate in the PPM project. The local platform of the Wrocław Medical University (PPM -UMW) in an institutional repository, which keeps the records and archives the research, scientific ...
openaire   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

GDPR and health research: stakeholder voices. Data protection and health research - what does the legislation mean for patients, the public and the research community? Report and recommendations. [PDF]

, 2018
This report presents the proceedings of the Irish Health Research Forum on November 14th 2018 focusing on data protection legislation and health research, and the implications for patients, the public and researchers.
Medical Research Charities Group
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

„Gong Głodomora” – humorystyczny obraz atmosfery intelektualnej i obyczajowości panującej w Zakładzie Przyrodoleczniczym doktora Apolinarego Tarnawskiego w Kosowie

Krakowskie Pismo Kresowe, 2018
Starveling’s Gong. A Humorous Portrayal of the Intellectual Atmosphere and Customs of the Natural Medicine Centre of Dr Apolinary Tarnawski in Kosow Starveling’s Gong is a unique copy of a satirical piece  in the form of a typewritten journal edited ...
Natalia Tarkowska
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology

Cell Reports, 2019
Summary: VPS10P domain receptors emerge as central regulators of intracellular protein sorting in neurons with relevance for various brain pathologies. Here, we identified a role for the family member SorCS2 in protection of neurons from oxidative stress
Anna R. Malik, Kinga Szydlowska, Karolina Nizinska, Antonino Asaro, Erwin A. van Vliet, Oliver Popp, Gunnar Dittmar, Raphaela Fritsche-Guenther, Jennifer A. Kirwan, Anders Nykjaer, Katarzyna Lukasiuk, Eleonora Aronica, Thomas E. Willnow   +12 more
doaj   +1 more source