Results 41 to 50 of about 220,770,914 (263)

Activity and function of auxiliary fluxes of glucose metabolism in response to physiological normoxia (5 % O2) during long-term Adipose-Derived Stem/Stromal cell culture

open access: yesEuropean Journal of Cell Biology
Energy metabolism homeostasis emerges as a dominant element influencing mesenchymal stem/stromal cells’ trajectory of development. The predominant glycolysis activity is a primary driver of cell proliferation and maintenance of the high-energetic state ...
Paulina Rybkowska   +6 more
doaj   +1 more source

Artificial meat? Feasible approach based on the experience from cell culture studies

open access: yesJournal of Integrative Agriculture, 2015
This short review is to list pros and cons which are based on the literature and personal experience in cell culture studies related to possible commercial production of artificial meat as functional food.
Arkadiusz Orzechowski
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Examples of data modules on the Wroclaw Medical University Polish Platform of Medical Research - worked schemes and development plans = Przykłady modułów danych na Polskiej Platformie Medycznej Uniwersytetu Medycznego we Wrocławiu - wypracowane schematy oraz plany rozwojowe

open access: yesForum Bibliotek Medycznych, 2023
Polish Platform of Medical Research (PPM) is a knowledge and research potential management platform for Polish academic institutions from the medical field which participate in the PPM project. The local platform of the Wrocław Medical University (PPM -UMW) in an institutional repository, which keeps the records and archives the research, scientific ...
openaire   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

GDPR and health research: stakeholder voices. Data protection and health research - what does the legislation mean for patients, the public and the research community? Report and recommendations. [PDF]

open access: yes, 2018
This report presents the proceedings of the Irish Health Research Forum on November 14th 2018 focusing on data protection legislation and health research, and the implications for patients, the public and researchers.
Medical Research Charities Group
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

„Gong Głodomora” – humorystyczny obraz atmosfery intelektualnej i obyczajowości panującej w Zakładzie Przyrodoleczniczym doktora Apolinarego Tarnawskiego w Kosowie

open access: yesKrakowskie Pismo Kresowe, 2018
Starveling’s Gong. A Humorous Portrayal of the Intellectual Atmosphere and Customs of the Natural Medicine Centre of Dr Apolinary Tarnawski in Kosow Starveling’s Gong is a unique copy of a satirical piece  in the form of a typewritten journal edited ...
Natalia Tarkowska
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology

open access: yesCell Reports, 2019
Summary: VPS10P domain receptors emerge as central regulators of intracellular protein sorting in neurons with relevance for various brain pathologies. Here, we identified a role for the family member SorCS2 in protection of neurons from oxidative stress
Anna R. Malik   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy