Results 21 to 30 of about 11,399 (257)

Effect of Long-Term 3D Spheroid Culture on WJ-MSC

Cells, 2021
The aim of our work was to develop a protocol enabling a derivation of mesenchymal stem/stromal cell (MSC) subpopulation with increased expression of pluripotent and neural genes.
Agnieszka Kaminska, Aleksandra Wedzinska, Marta Kot, Anna Sarnowska   +3 more
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Neurogenic and Neuroprotective Potential of Stem/Stromal Cells Derived from Adipose Tissue

Cells, 2021
Currently, the number of stem-cell based experimental therapies in neurological injuries and neurodegenerative disorders has been massively increasing.
Anna Figiel-Dabrowska, Klaudia Radoszkiewicz, Paulina Rybkowska, Natalia Ewa Krzesniak, Dorota Sulejczak, Anna Sarnowska   +5 more
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Assessment of the Dose-Dependent Effect of Human Platelet Lysate on Wharton’s Jelly-Derived Mesenchymal Stem/Stromal Cells Culture for Manufacturing Protocols

Stem Cells and Cloning: Advances and Applications
Aleksandra Bzinkowska, Anna Sarnowska Translational Platform for Regenerative Medicine, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, PolandCorrespondence: Anna Sarnowska, Mossakowski Medical Research Institute, Pawinskiego ...
Bzinkowska A, Sarnowska A
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The Metabolic Changes between Monolayer (2D) and Three-Dimensional (3D) Culture Conditions in Human Mesenchymal Stem/Stromal Cells Derived from Adipose Tissue

Cells, 2023
Introduction: One of the key factors that may influence the therapeutic potential of mesenchymal stem/stromal cells (MSCs) is their metabolism. The switch between mitochondrial respiration and glycolysis can be affected by many factors, including the ...
Paulina Rybkowska, Klaudia Radoszkiewicz, Maria Kawalec, Dorota Dymkowska, Barbara Zabłocka, Krzysztof Zabłocki, Anna Sarnowska   +6 more
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The Synaptic Dysregulation in Adolescent Rats Exposed to Maternal Immune Activation

Frontiers in Molecular Neuroscience, 2021
Maternal immune activation (MIA) is a risk factor for neurodevelopmental disorders in offspring, but the pathomechanism is largely unknown. The aim of our study was to analyse the molecular mechanisms contributing to synaptic alterations in hippocampi of
Magdalena Cieślik, Magdalena Gassowska-Dobrowolska, Aleksandra Zawadzka, Małgorzata Frontczak-Baniewicz, Magdalena Gewartowska, Agnieszka Dominiak, Grzegorz A. Czapski, Agata Adamczyk   +7 more
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A different approach to accessibility, i.e. WCAG in full-text documents – working with files

Forum Bibliotek Medycznych, 2021
Polish Platform of Medical Research provides open access to scientific resources, including full text publications, PhD theses and other repository documents.
Monika Fiedorowicz, Agnieszka Janucik
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Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord

Stem Cells International, 2020
Objective. Bone defects or atrophy may arise as a consequence of injury, inflammation of various etiologies, and neoplastic or traumatic processes or as a result of surgical procedures.
Michal Kosinski, Anna Figiel-Dabrowska, Wioletta Lech, Lukasz Wieprzowski, Ryszard Strzalkowski, Damian Strzemecki, Lukasz Cheda, Jacek Lenart, Krystyna Domanska-Janik, Anna Sarnowska   +9 more
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Myelin-Independent Therapeutic Potential of Canine Glial-Restricted Progenitors Transplanted in Mouse Model of Dysmyelinating Disease

Cells, 2021
Background: Dysfunction of glia contributes to the deterioration of the central nervous system in a wide array of neurological disorders, thus global replacement of glia is very attractive.
Luiza Stanaszek, Malgorzata Majchrzak, Katarzyna Drela, Piotr Rogujski, Joanna Sanford, Michal Fiedorowicz, Magdalena Gewartowska, Malgorzata Frontczak-Baniewicz, Piotr Walczak, Barbara Lukomska, Miroslaw Janowski   +10 more
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Understanding Intra- and Inter-Species Variability in Neural Stem Cells’ Biology Is Key to Their Successful Cryopreservation, Culture, and Propagation

Cells, 2023
Although clinical trials on human neural stem cells (hNSCs) have already been implemented in the treatment of neurological diseases and they have demonstrated their therapeutic effects, many questions remain in the field of preclinical research regarding
Klaudia Radoszkiewicz, Katarzyna Jezierska-Woźniak, Tomasz Waśniewski, Anna Sarnowska   +3 more
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Case Report: Further Delineation of Neurological Symptoms in Young Children Caused by Compound Heterozygous Mutation in the PIEZO2 Gene

Frontiers in Genetics, 2021
PIEZO2 protein is a unique ion channel that converts mechanical impulses into cellular signals in somatosensory neurons and is involved in various mechanotransduction pathways. The recessive PIEZO2 loss-of-function pathogenic variants are associated with
Magdalena Klaniewska, Maria Jedrzejowska, Malgorzata Rydzanicz, Justyna Paprocka, Mateusz Biela, Ewelina Wolanska, Agnieszka Pollak, Emilia Debek, Maria Sasiadek, Rafal Ploski, Monika Gos, Robert Smigiel   +11 more
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