Results 31 to 40 of about 178,574,484 (267)

Unraveling the impact of human cerebrospinal fluid on human neural stem cell fate

Frontiers in Cell and Developmental Biology
Human neural stem/progenitor cells (hNSCs) can potentially treat neurological diseases, but their low survival and proliferation rates after transplantation remain challenging.
Klaudia Radoszkiewicz, Aleksandra Bzinkowska, Monika Sypecka, Dorota Sulejczak, Daniela Ferrari, Maurizio Gelati, Angelo Luigi Vescovi, Angelo Luigi Vescovi, Anna Sarnowska   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Clinical cell therapy guidelines for neurorestoration (IANR/CANR 2022)☆

Journal of Neurorestoratology, 2022
Cell therapy has been shown to be a crucial clinical therapeutic option for central nervous system diseases or damage. Promoting standardization of clinical cell therapy procedures is essential for professional associations devoted to cell therapy.
Hongyun Huang, Ziad M. Al Zoubi, Gustavo Moviglia, Hari Shanker Sharma, Anna Sarnowska, Paul R. Sanberg, Lin Chen, Qun Xue, Dario Siniscalco, Shiqing Feng, Hooshang Saberi, Xiaoling Guo, Mengzhou Xue, Milan R. Dimitrijevic, Russell J. Andrews, Gengsheng Mao, Robert Chunhua Zhao, Fabin Han   +17 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Assessment of the effectiveness of medical simulators in the practical training of medical students: Preliminary results in MU-Varna [PDF]

, 2019
INTRODUCTION: Nowadays, simulators have become part of most medical universities’ educational strategy. In recent years, Medical University of Varna has been equipped with the most modern medical simulators, aiming to meet the practical training needs of
Chernogorova, Yanita; Medical University of Varna, Grancharov, Deyan; Medical University of Varna, Bliznakov, Zhivko; Medical University of Varna   +2 more
core   +7 more sources

Polish Contribution to the Development of Views on Horse Riding as a Form of Therapy – a Brief Historical Retrospection

Central European Journal of Sport Sciences and Medicine, 2018
Since ancient times, man has ridden horses. Ancient Greeks and Romans, who did so mostly for utilitarian purposes, also found that horse riding was the source of rider’s health, recommending equestrianism to men and women of different ages as an exercise
Renata Urban
doaj   +1 more source

FEASIBILITY STUDY OF INEXPENSIVE THERMAL SENSORS AND SMALL UAS DEPLOYMENT FOR LIVING HUMAN DETECTION IN RESCUE MISSIONS APPLICATION SCENARIOS [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Significant efforts are invested by rescue agencies worldwide to save human lives during natural and man-made emergency situations including those that happen in wilderness locations.
E. Levin, A. Zarnowski, J. L. McCarty, J. Bialas, A. Banaszek, S. Banaszek   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source