Results 61 to 70 of about 30,654 (315)
By bringing together a sophisticated conceptualization of political trustworthiness (integrated model of trust) with theorizing from information processing (trait inferences, inclusion-exclusion model), our research aimed at investigating the impact of a
Anna Halmburger +2 more
doaj +1 more source
CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source
Caps on Political Contributions, Monetary Penalties and Politician Preferences [PDF]
With politician preferences over policy outcomes, the effect of a contribution cap with monetary penalties for exceeding the cap is starkly different from the case with an indifferent politician.
Tuvana Pastine, Ivan Pastine
core
Marina Oswald & Kathleen Wade: Wives Involved in a Political Ambition
“I’m no psychiatrist, but if you ask me, politicians in general are pretty insecure people” (O’Brien, 1994, p. 97). This quotation describes politicians as insecure people, and the word “insecure” has more than one implication.
أ.م .د. رشا عبد المنعم عزيز
doaj +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Politician-Proof Policy? [PDF]
In this paper I discuss the nature of the political constraints that the World Bank faces in delivering basic services to the poor. The main problem arises because the Bank has to work through domestic governments which have political aims different from
Robinson James A.
core
Ultrasound‐Actuated Gene Editing in Human Kidney Organoids
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller +6 more
wiley +1 more source
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
The Politician and his Banker [PDF]
Should the European Union grant state aid through an institution like the European Investment bank? This paper evaluates the efficiency of different measures for granting state aid.
Hendrik Hakenes, Christa Hainz
core

