Results 81 to 90 of about 30,654 (315)

Politician trojan horse issue

Jurnal Civics: Media Kajian Kewarganegaraan
This article examines the concept of "Trojan Horse politics" and the challenges associated with priority-based political development in the context of the 2024 simultaneous elections, using an ethical Trojan Horse strategy from a political philosophy ...
Yakobus Ndona, Liber Siagian, Elisa Br Ginting, Gabriel Faimau   +3 more
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Divisive Politics and Accountability [PDF]

The paper analyzes a political accountability game with an electorate of 'partisan' and 'independent' voters. It is shown that politicians have a strategic incentive to engage in 'divisive politics', that is, to force some independent voters to take ...
Aron Kiss
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Politician Preferences and Caps on Political Lobbying [PDF]

This paper extends Che and Gale (1998) by allowing the incumbent politician to have a preference for the policy position of one of the lobbyists. The effect of a contribution cap is analyzed where two lobbyists contest for a political prize.
Tuvana Pastine, Ivan Pastine
core   +1 more source

The Politics of Ethics: Can Honesty Cross Over Political Polarization?

Journalism and Media
This research demonstrates how confirmation and disconfirmation biases manifest based on individuals’ political affiliations when processing a self-disclosure message in the context of a political crisis. An experiment presented a crisis message in which
Sang Lee, Samar Ben Romdhane
doaj   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

Advanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng, Qi Yang, Jinze Li, Fuqiang Ma, Xuefeng Wang, Zhen Guo, Chuanyu Li, Dongshu Li, Jia Yao, Zhiqi Zhang, Wei Zhang, Lianqun Zhou   +11 more
wiley   +1 more source

Pemilu 2014: Politisi Pencari Kursi di Senayan

Jurnal Transformative, 2018
General Elections can be used as evidence as well as evaluation of the recruitment process, political circulation. This paper proves that in the 2014 Election there has been a stagnation in political circulation.
Fathur Rahman, Irma Fitriana Ulfah, Oscar Radyan Danar   +2 more
doaj   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

Politician's Reputation and Policy (Un)persistence [PDF]

We consider a political career concern model where politicians differ in their information on the states of the world in different periods and the outcome of a policy in different periods depends on the same state of the world.
Iconio Garrì
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