Results 71 to 80 of about 30,654 (315)
, 2022 Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
openaire +2 more sources
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
Problems of creation and functioning clusters associations
Путеводитель предпринимателя, 2020 In the article problems and experience of creation and functioning of industrial clusters are considered. The special conditions, characteristic competitive advantages therefore the measures undertaken for creation of a cluster have to consider these ...
D. V. Skvirya
doaj
Advanced Science, EarlyView.MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou +21 more
wiley +1 more source
Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Becoming a politician: A biography of James Cope
, 1997 This work documents the personal life and contextual events surrounding an ordinary man in order to investigate the history of his development and education both as a person and as a politician.
Cope, Robert G.
core
Dinamika Islam Politik di Indonesia pada Era Reformasi (1998-2001)
Al-Jami'ah: Journal of Islamic Studies, 2003 This article discusses the political attitude of some Indonesian Muslims to the reformation era of Indonesia. Euphorically, they responded the reformation in the same way as in the early history of Indonesian politics, i.e., they are interested much in ...
Kamaruzzaman Bustamam-Ahmad
doaj +1 more source
Genetic Code Expanded T Cell for Controllable Immunotherapy
Advanced Science, EarlyView.Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang +4 more
wiley +1 more source