Results 41 to 50 of about 1,096,453 (298)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Politics of Curriculum Design in Instructional Communication in Ghana [PDF]

Athens Journal of Mass Media and Communications, 2018
This paper presents findings from a two-year ethnographic study that explored how institutional politics shaped the curriculum of a graduate program in instructional communication in a Ghanaian public university.
Wincharles Coker
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

[Review of] Paul M. Sniderman and Thomas Piazza. The Scar of Race [PDF]

, 1994
Into the murky, politically-charged waters of contemporary racial politics shines this welcome ray of light. Paul M. Sniderman and Thomas Piazza, using clever research design and innovative techniques, clarify the changing meaning of race in today’s ...
Goldstein-Shirley, David
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

From authority to similarity: How Google transformed its knowledge infrastructure using computer vision

Big Data & Society
We investigate the impact of computer vision models, a prominent artificial intelligence tool, on critical knowledge infrastructure, using the case of Google search engines.
Warren Pearce, Maud Borie, Laura Bruschi, Daniele Dell'Orto, Matthew Hanchard, Elena Pilipets, Alessandro Quets, Zijing Xu   +7 more
doaj   +1 more source

Dis/re-orienting design through norm-critical gender lenses: an educational case in Turkey

Frontiers in Sociology
Design, as a practice of developing solutions beyond products, and increasingly services and policies, inevitably poses an impact on gender (in)equality which remains largely unrecognized by design practitioners.
Erman Örsan Yetiş, Yekta Bakırlıoğlu, Yekta Bakırlıoğlu   +2 more
doaj   +1 more source

The Instruments of Place Branding: How is it Done? [PDF]

, 2009
Place branding is the idea of discovering or creating some uniqueness, which differentiates one place from others in order to gain a competitive brand value.
Ashworth, Gregory
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Intersubjectivity as an analytical concept to study human-animal interaction in historical context: street dogs in Late Ottoman period

Frontiers in Sociology
Human knowledge pertaining to human-animal interaction is constructed by the human author, albeit the presence of animal subjects. Such a human lens is pronounced when studying human-animal interactions across history, whose nonhuman animal subjects are ...
Burak Taşdizen, Erman Örsan Yetiş, Yekta Bakırlıoğlu   +2 more
doaj   +1 more source