Results 61 to 70 of about 1,096,453 (298)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Neighbourhoodies: courageous community, colours, blazing bling and defiant delight [PDF]

open access: yes, 2010
As we see a global culture appear across the planet identity politics simultaneously gravitate towards issues of the local. In society’s top strata people strive to live in posh areas with the right postal code. Subversive counterculture activists try to
von Busch, Otto
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

spotlight no. 5, 2018 - #SmartHealthSystems Digitalization requires an effective strategy, compelling political leadership and a coordinating institution with a national mandate [PDF]

open access: yes, 2018
In terms of digitalizing its healthcare sector, Germany trails far behind several other countries as the potential for quality and efficiency in German healthcare remains untapped ●● Countries that are succeeding in digitalizing their healthcare systems ...
Kostera, Thomas, Thranberend, Timo
core  

Unfolding the Political Capacities of Design

open access: yesDiseña, 2015
The aim of this article is to discuss the political capacities of design. The usual way of exploring the relation between design and politics has focused on design’s ability to enfold the political, that is, to inscribe political codes into things, places, and bodies, operating at a sub-political level.
Domínguez Rubio, Fernando   +1 more
openaire   +7 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Survey on Computational Politics

open access: yesIEEE Access, 2020
Computational Politics is the study of computational methods to analyze and moderate users' behaviors related to political activities such as election campaign persuasion, political affiliation, and opinion mining.
Ehsan Ul Haq   +3 more
doaj   +1 more source

Social Housing - Housing the Social: Art, Property and Spatial Justice [PDF]

open access: yes, 2012
Social Housing - Housing the Social: Art, Property and Spatial Justice examines ongoing transformations in social housing and asks how these transformations are reflected in the aspirations and practices of artists.

core  

Liberating clocks: Developing a critical horology to rethink the potential of clock time [PDF]

open access: yes, 2017
Across a wide range of cultural forms, including philosophy, cultural theory, literature and art, the figure of the clock has drawn suspicion, censure and outright hostility.
Bastian, Michelle
core   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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