Results 111 to 120 of about 16,153 (200)

Ratiometric pH‐Responsive and Biomimetic Microparticles for Quantitative Monitoring of Phagosomal Acidification

Chemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis, Héloïse Uhl, Florence Niedergang, Jacques Fattaccioli, Blaise Dumat, Jean‐Maurice Mallet   +5 more
wiley   +1 more source

Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells

Viruses
Despite extensive efforts, no highly effective antiviral molecule exists for treating moderate and severe COVID-19. Nanotechnology has emerged as a promising approach for developing novel drug delivery systems to enhance antiviral efficacy.
Eduardo Ricci-Junior, Alice Santos Rosa, Tatielle do Nascimento, Ralph Santos-Oliveira, Marcos Alexandre Nunes da Silva, Debora Ferreira Barreto-Vieira, Luísa Tozatto Batista, Giovanna Barbosa da Conceição, Tayane Alvites Nunes Quintão, Vivian Neuza Santos Ferreira, Milene Dias Miranda   +10 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, Volume 15, Issue 36, 25 September 2026.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Development and Evaluation of in situ eye gel for delivery of gatifloxacin and betamethasone sodium phosphate

Al-Mustansiriyah Journal of Pharmaceutical Sciences
Drug delivery to ocular tissues is challenging due to the rapid removal of instilled drugs due to the low resident time in ocular tissues. The study aimed to formulate an ophthalmic in situ gel that delivers two drugs (betamethasone sodium phosphate ...
Fatima Mustafa Ali, Athmar Dhahir Habeeb Al-Shohani, Asma Buanz   +2 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Physico-chemical properties of poloxamer surfactants related to their adsorption

, 1996
The properties of poloxamer surfactants were investigated by a number of techniques. The adsorption of P188, P338 and P407, was studied on range of solids. The solids used were hydrophobic and poorly water soluble.
Carthew, David Leonard
core  

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Polyphenol‐Based Biomaterials for Antibacterial Infection Management: From Assembly Chemistry to Infection Site‐Specific Therapeutic Platforms

cMat, Volume 3, Issue 3, September 2026.
Polyphenol assembly chemistry provides a versatile basis for antibacterial biomaterials. Matching material format and function to the distinct barriers of wound, respiratory, intestinal, and implant‐associated infections is central to effective and translatable design. ABSTRACT Bacterial infections involving multidrug‐resistant pathogens and persistent
Wei Yang, Li Wan, Ming Wen, Haiyan He, Hongliang Tan   +4 more
wiley   +1 more source

Analgesic Effect of Sulforaphane: A New Application for Poloxamer-Hyaluronic Acid Hydrogels

Gels
Sulforaphane (SFN) has shown potential as an antioxidant and anti-inflammatory agent. To improve its druggability, we developed new analgesic formulations with sulforaphane-loaded hyaluronic acid (HA)-poloxamer (PL) hydrogel. This study evaluated the pre-
Juliana Zampoli Boava Papini, Bruno de Assis Esteves, Vagner Gomes de Souza Oliveira, Henrique Ballassani Abdalla, Cintia Maria Saia Cereda, Daniele Ribeiro de Araújo, Giovana Radomille Tofoli   +6 more
doaj   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source