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Production of ultra‐high‐molecular‐weight poly‐γ‐glutamic acid by a newly isolated Bacillus subtilis strain and genomic and transcriptomic analyses

Biotechnology Journal
Poly‐γ‐glutamic acid (γ‐PGA) is a microbial‐derived polymer with molecular weight (Mw) from 104 to 107 Da, and the high‐Mw (> 7.0 × 105 Da) or ultra‐high‐Mw (> 5.0 × 106 Da) γ‐PGA has important application value as a tissue engineering material, as a ...
Wei Zeng   +5 more
semanticscholar   +1 more source

Incorporation of poly(γ-glutamic acid) in lipid nanoparticles for enhanced mRNA delivery efficiency in vitro and in vivo.

Acta Biomaterialia
Messenger RNA (mRNA)-based therapy shows immense potential for broad biomedical applications. However, the development of safe and efficacious mRNA delivery vectors remains challenging due to delivery barriers and inefficient intracellular payload ...
Hongqian Zhang   +5 more
semanticscholar   +1 more source

Adaptive injectable carboxymethyl cellulose/poly (γ-glutamic acid) hydrogels promote wound healing.

Biomaterials Advances, 2022
The clinical acceleration of skin autogenous healing remains a great challenge, especially in the early stage after injury. In this work, a novel directly injectable hydrogel with high self-adaptability is designed as a provisional matrix to close the ...
W. Zhang   +6 more
semanticscholar   +1 more source

Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects.

International Journal of Biological Macromolecules
Three genes involved in poly-γ-glutamic acid(γ-PGA)synthesis cloned from Bacillus licheniformis were transformed into cucumber for the first time. Compared with control, its water content increased by 6-14 % and water loss rate decreased by 11-12 %.
Can Li   +10 more
semanticscholar   +1 more source

Soil macropore characteristics and aggregate stability with poly‐γ‐glutamic acid amendment under wetting–drying cycles

European Journal of Soil Science, 2023
Soils are typically subjected to multiple wetting–drying (WD) cycles due to irrigation and seasonal climate cycles, which directly impact soil pore structure and soil aggregate stability.
Lu Liu   +4 more
semanticscholar   +1 more source

Enhanced poly-γ-glutamic acid synthesis in Corynebacterium glutamicum by reconstituting PgsBCA complex and fermentation optimization.

Metabolic Engineering, 2023
Previously, a novel Corynebacterium glutamicum strain for the de novo biosynthesis of tailored poly-γ-glutamic acid (γ-PGA) has been constructed by our group.
Guoqiang Xu   +11 more
semanticscholar   +1 more source

Anionic polypeptide poly(γ-glutamic acid)-functionalized magnetic Fe3O4-GO-(o-MWCNTs) hybrid nanocomposite for high-efficiency removal of Cd(II), Cu(II) and Ni(II) heavy metal ions

Chemical Engineering Journal, 2018
A novel hybrid adsorbent, anionic polypeptide poly(γ-glutamic acid)—(γ-PGA) functionalized magnetic Fe3O4-GO-(o-MWCNTs) hybrid nanocomposite was successfully prepared via a simple one-pot reaction.
Lu Wang   +7 more
semanticscholar   +1 more source

A Dual Network Hydrogel Sunscreen Based on Poly-γ-glutamic acid/Tannic Acid Demonstrates Excellent Anti-UV, Self-Recovery and Skin-Integration Capacities.

ACS Applied Materials and Interfaces, 2019
Novel sunscreen products based on bioadhesive/gel systems that can prevent the skin penetration behaviors of UV filters have attracted increasing attention in recent years.
Rui Wang   +7 more
semanticscholar   +1 more source

Effects of poly-γ-glutamic acid on water use efficiency, cotton yield, and fiber quality in the sandy soil of southern Xinjiang, China

Agricultural Water Management, 2019
Poly-γ-glutamic acid (γ-PGA) is a promising, environmentally friendly, non-toxic, biodegradable, and super water-absorbable polymer. Using γ-PGA in agriculture is of great significance to promote crop growth, save irrigation water, and cope with water ...
Jiaping Liang   +4 more
semanticscholar   +1 more source

Enhanced production of poly‐γ‐glutamic acid by improving ATP supply in metabolically engineered Bacillus licheniformis

Biotechnology and Bioengineering, 2018
Poly‐γ‐glutamic acid (γ‐PGA) is an important multifunctional biopolymer with various applications, for which adenosine triphosphate (ATP) supply plays a vital role in biosynthesis.
D. Cai   +10 more
semanticscholar   +1 more source

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