Results 131 to 140 of about 16,681,036 (304)

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen, Xiaoxiao Chen, Baozhu Yang, Hui Xu, Xueting Sun, Hongkai Qi, Huilin Hu, Ronghua Wu, Fengkai Qiu, Bing Wu, Yu Luo, Gaofeng Shu, Jiansong Ji   +12 more
wiley   +1 more source

Phase‐Programmed Microneedles Enable Sequential Hydrogen and Quercetin Release for Scar‐Reduced Regeneration of Burn Wounds

Advanced Science, EarlyView.
A phase‐programmed microneedle patch, comprising a poly (lactic‐co‐glycolic acid) (PLGA) shell and a sulfobutylether‐β‐cyclodextrin (SBECD) core, is designed for sequential hydrogen and quercetin release for scar‐reduced regeneration of burn wounds. ABSTRACT Burn wounds complicated by bacterial infection and fibrotic scarring remain a major clinical ...
Yongnian Zeng, Zhigang Chu, Huiyuan Yang, Wen Zhang, Peng Jiang, Jiapeng Lei, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

ATMOSPHERIC PLASMA SURFACE MODIFICATION OF ELECTROSPUN POLY(L-LACTIC ACID): EFFECT ON MAT PROPERTIES AND CELL CULTURING

, 2012
Atmospheric Plasma Surface Modification of Electrospun Poly(L-lactic acid): Effect on Mat Properties and Cell ...
R Laurita, L Calzà, E Ghedini, LS Dolci, A Zucchelli, ML Focarete, A Fiorani, A Liguori, M Alessandri, V Colombo, P Sanibondi, S D Quiroga, M Gherardi   +12 more
core  

Integrated Single‐Cell and Spatial Transcriptomics Reveal Convergence on a Senescence‐Associated B Cell–MIF Signaling Axis in Joint Aging and Osteoarthritis Progression

Advanced Science, EarlyView.
Single‐cell and spatial transcriptomics implicate senescent B cells and macrophage migration inhibitory factor (MIF) signaling in aging and osteoarthritic joints. An injectable hydrogel combining quercetin with siRNA targeting MIF attenuates cartilage degeneration in a mouse model of osteoarthritis.
Weida Li, Yi Wang, Yongqing You, Yue Cui, Jiayun Liu, Xingbiao Ma, QiuYu Zhu, Qiang Wu, Zanjing Zhai, Zuyan Lu, Kerong Dai, Ye Sun   +11 more
wiley   +1 more source

Bridging Performance and Fate: A Framework for Sustainable, Composite‐Based Flexible Electronic Systems

Advanced Electronic Materials, EarlyView.
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley   +1 more source

Consensus Recommendations for the Reconstitution and Aesthetic Use of Poly-D,L-Lactic Acid Microspheres – Comment on the Reason of “Fast Reconstitution” [Response to Letter]

Clinical, Cosmetic and Investigational Dermatology
Fabiano Nadson Magacho-Vieira1,2 1Department of Clinical, Aesthetic and Surgical Dermatology, Batista Memorial Hospital, Rua Professor Dias da Rocha 1530, Fortaleza, CE, 60170-311, Brazil; 2Magacho Institute for Health Education, Av.
Magacho-Vieira FN
doaj  

Synthesis, characterization of poly l(+) lactic acid and its application in sustained release of isosorbide dinitrate

Scientific Reports
Poly l(+) lactic acid (PLLA) has become crucial in the biomedical industry for various uses. The direct polycondensation method was used to prepare Poly l(+) Lactic Acid (PLLA).
El-Refaie Kenawy, A. M. Abd El.Hay, Nermeen Saad, Mohamed M. Azaam, Kamel R. Shoueir   +4 more
doaj   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Consensus Recommendations for the Reconstitution and Aesthetic Use of Poly-D,L-Lactic Acid Microspheres – Comment on the Reason of “Fast Reconstitution” [Letter]

Clinical, Cosmetic and Investigational Dermatology
Jui-Yu Lin, Chuan-Yuan Lin Li-An Medical Clinic, Taipei City, 104452, TaiwanCorrespondence: Chuan-Yuan Lin, Li-An Medical Clinic, 4F., No. 267, Lequn 2 nd Road, Zhongshan Dist, Taipei City, 104452, Taiwan, Tel +886-939642621, Email linchuanyuan@doctortou.
Lin JY, Lin CY
doaj  

The effects of poly L-lactic acid nanofiber scaffold on mouse spermatogonial stem cell culture

International Journal of Nanomedicine, 2013
Neda Eslahi,1,2,* Mahmoud Reza Hadjighassem,1,3 Mohammad Taghi Joghataei,1,2 Tooba Mirzapour,4 Mehrdad Bakhtiyari,1,2 Malak Shakeri,5 Vahid Pirhajati,1,2 Peymaneh Shirinbayan,6,* Morteza Koruji1,21Cellular and Molecular Research Center, Iran University ...
Eslahi N, Hadjighassem MR, Joghataei MT, Mirzapour T, Bakhtiyari M, Shakeri M, Pirhajati V, Shirinbayan P, Koruji M   +8 more
doaj