Results 201 to 210 of about 145,382 (250)
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Interaction of methylglyoxal with poly-l-lysine
Biomaterials, 1980The reaction of methylglyoxal with polypeptides is accompanied by an electron spin resonance absorption in the free radial region. Analysing the interaction of methylglyoxal with poly-L-lysine we found that methylglyoxal polymer formation is a major process in our system.
G, Szabo, J C, Kertesz, K, Laki
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Archives of Biochemistry and Biophysics, 1980
Abstract Coupling the cathepsin D inhibitor pepstatin to poly( l -Lys) ( M r 13,000) is shown to enhance its inhibition of protein breakdown in whole cell systems. Rates of intracellular protein breakdown for prelabeled proteins of Balb/c 3T3 fibroblasts were measured in the presence and absence of amino acids and insulin to generate basal and ...
P, Campbell, G I, Glover, J M, Gunn
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Abstract Coupling the cathepsin D inhibitor pepstatin to poly( l -Lys) ( M r 13,000) is shown to enhance its inhibition of protein breakdown in whole cell systems. Rates of intracellular protein breakdown for prelabeled proteins of Balb/c 3T3 fibroblasts were measured in the presence and absence of amino acids and insulin to generate basal and ...
P, Campbell, G I, Glover, J M, Gunn
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Transdermal delivery of poly-l-lysine by sonomacroporation
Ultrasound in Medicine & Biology, 2002A feasibility study of using high-amplitude ultrasound (US) to deliver large molecules transdermally was undertaken. US (20 kHz) of intensity in the range between 2 to 50 W/cm(2) was used to increase the permeability of skin in vitro to large size molecules. For example, when 20-kHz, 5% duty cycle US at the spatial average and pulse-average intensity I(
Ludwig J, Weimann, Junru, Wu
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Interaction of poly-l-lysine and nucleic acids
Journal of Molecular Biology, 1966Interactions of poly- L -lysine with poly (I + C) and with thymus DNA in dilute solutions and in low ionic strength have been studied. The helix-coil transition of the polynucleotides in the reaction was followed by optical density at 248 mμ, or 260 mμ Both of these poly- L -lysine plus polynucleotide solutions gave a two-step transition, one of which (
M, Tsuboi, K, Matsuo, P O, Ts'o
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The structure of poly-l-lysine in different solvents
Biophysical Chemistry, 2013Understanding the factors that affect the conformational stability of the polypeptide main chain provides insight not only into the molecular basis of unfolded states but also into the earliest event that occurs during the protein folding. The presented study was concentrated on finding the conformational distributions of poly-L-lysine (PLL) by ...
Andreja, Mirtič, Jože, Grdadolnik
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Evidence for dissociation of ferrihemoglobin by poly-L-lysine
Experientia, 1979Circular dichroism and absorption spectra of ferrihemoglobin were shown to be altered upon binding with poly-L-lysine at alkaline pH. When ferrihemoglobin immobilized to Sepharose gel was treated with poly-L-lysine, hemoglobin subunits were released from the gel. These results suggest that ferrihemoglobin was dissociated into subunits by poly-L-lysine.
K, Imai, T, Yoshimura
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Rapid Prototyping of Patterned Poly-L-Lysine Microstructures
2006 International Conference of the IEEE Engineering in Medicine and Biology Society, 2006For applications in cell biology, the ability to produce patterns of adhesion proteins for directing cell patterning is of particular interest. Often though, these patterns require extensive clean room facilities and intricate chrome masks to achieve very small feature sizes.
Jiwan Kim, Justin C. Williams
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Wei sheng wu xue bao = Acta microbiologica Sinica, 2011
Epsilon-Poly-L-lysine (epsilon-PL) is a polymer with strong antimicrobial activity and consists of 25-35 L-lysine monomers linked via epsilon-amino-alpha-carboxyl peptide bond. This polymer is one of only two homo-poly (amino acid) polymers known in nature. To date, the biosynthesis mechanism of epsilon-PL was remained unclear.
Qingping, Wu +2 more
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Epsilon-Poly-L-lysine (epsilon-PL) is a polymer with strong antimicrobial activity and consists of 25-35 L-lysine monomers linked via epsilon-amino-alpha-carboxyl peptide bond. This polymer is one of only two homo-poly (amino acid) polymers known in nature. To date, the biosynthesis mechanism of epsilon-PL was remained unclear.
Qingping, Wu +2 more
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Electron microscopy of the poly-l-lysine α-helix
Ultramicroscopy, 1982Dark field electron micrographs of polylysine molecules in the alpha-helical form were analyzed by digital Fourier techniques to determine the extent to which the helix was still represented in the images. A total of 50 molecular images were selected following defined criteria, 13 from spreads of molecules from aqueous solution and 37 from methanol ...
D W, Andrews, F P, Ottensmeyer
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Resveratrol modulates fibrillogenesis in a poly‑l‑lysine peptide
International Journal of Biological Macromolecules, 2019Resveratrol (Res) is an effective inhibitor of amyloid fibril formation and reduces neuron cell toxicity. The effect of Res on the fibrillogenesis of a polar polypeptide, poly‑l‑lysine (PLL), was studied by Fourier-transform infrared spectroscopy, vibrational circular dichroism and transmission electron microscopy.
Katarzyna, Cieślik-Boczula +1 more
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