Results 21 to 30 of about 145,382 (250)

Data describing the swelling behavior and cytocompatibility of biodegradable polyelectrolyte hydrogels incorporating poly(L-lysine) for applications in cartilage tissue engineering

Data in Brief, 2016
This data article presents data associated with the research article entitled “Evaluation of cell-laden polyelectrolyte hydrogels incorporating poly(L-lysine) for applications in cartilage tissue engineering” (Lam et al., 2016) [1].
Johnny Lam, Elisa C. Clark, Eliza L.S. Fong, Esther J. Lee, Steven Lu, Yasuhiko Tabata, Antonios G. Mikos   +6 more
doaj   +1 more source

Antimicrobial action of .EPSILON.-poly-L-lysine.

The Journal of Antibiotics, 1984
The antimicrobial spectrum of epsilon-poly-L-lysine (n = 25-30, epsilon-PL) was investigated by comparison with alpha-poly-L-lysine (n = 50, alpha-PL). epsilon-PL showed antimicrobial activity against Gram-positive and -negative bacteria at concentrations of 1-8 micrograms/ml. alpha-PL was less active than epsilon-PL.
S, Shima, H, Matsuoka, T, Iwamoto, H, Sakai   +3 more
openaire   +3 more sources

Development of liver-specific ribavirin-loaded nanoparticles with reduced cytotoxicity

Cogent Medicine, 2017
Ribavirin is widely used in several types of combination chemotherapy for the treatment of chronic hepatitis C. In order to deliver ribavirin to the liver and reduce its side effects, we previously prepared ribavirin monophosphate (RMP)-loaded ...
Kohei Kaneko, Tsutomu Ishihara
doaj   +1 more source

Improved biocompatibility and efficient labeling of neural stem cells with poly(L-lysine)-coated maghemite nanoparticles

Beilstein Journal of Nanotechnology, 2016
Background: Cell tracking is a powerful tool to understand cellular migration, dynamics, homing and function of stem cell transplants. Nanoparticles represent possible stem cell tracers, but they differ in cellular uptake and side effects.
Igor M. Pongrac, Marina Dobrivojević, Lada Brkić Ahmed, Michal Babič, Miroslav Šlouf, Daniel Horák, Srećko Gajović   +6 more
doaj   +1 more source

In Vitro Evaluation of Lipopolyplexes for Gene Transfection: Comparing 2D, 3D and Microdroplet-Enabled Cell Culture

Molecules, 2020
Complexes combining nucleic acids with lipids and polymers (lipopolyplexes) show great promise for gene therapy since they enable compositional, physical and functional versatility to be optimized for therapeutic efficiency.
Juan L. Paris, Filipe Coelho, Alexandra Teixeira, Lorena Diéguez, Bruno F. B. Silva, Sara Abalde-Cela   +5 more
doaj   +1 more source

Application of Sensitive Sensor Modified with MWNTs/Al2O3/poly-L-lysine Composite for 17β –estradiol Determination in Pregnant Woman Blood

International Journal of Electrochemical Science, 2018
A novel disposable sensor modified with MWNTs/Al2O3/poly-L-lysine film was developed for detection of clinical 17β-estradiol (17β-E2) urine samples in this study.
Yuting Wang, Ying Xiong, Hui Tian, Shi Wang, Qianying Zhang, Mingjing Zhang, Hong Ding, Ye Gu, Anlin Peng   +8 more
doaj   +1 more source

Comparison of different cationic polymers efficacy in fabrication of alginate multilayer microcapsules

Asian Journal of Pharmaceutical Sciences, 2020
In past decades, alginate-based multilayer microcapsules have been given important attention in various pharmaceutical investigations. Alginate-poly l lysine-alginate (APA) is studied the most.
Fariba Hajifathaliha, Arash Mahboubi, Leila Nematollahi, Elham Mohit, Noushin Bolourchian   +4 more
doaj   +1 more source

DERIVATIZACIÓN Y CARACTERIZACIÓN ESPECTROSCÓPICA DE UN BIOPOLÍMERO A BASE DE L -LISINA CON ANÁLOGOS DE LA D-BIOTINA: CO -POLI(L-LISINA)-GRAFT -(ε-N-[X-D -BIOTINIL]-L-LISINA)

Química Nova, 2016
We report the single-step derivatization reaction of a biopolymer based onL -lysine with D -biotin analogs:Co -poly(L -lysine)-graft-(ε-N -[X-D-biotinyl]-L -lysine) (PLL-X-Biotin).
Flavio Dolores Martínez-Mancera, José Luis Hernández-López   +1 more
doaj   +1 more source

In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-l-lysine and poly-l-lysine/poly-l-glutamate in rats

Journal of Materials Science: Materials in Medicine, 2014
The combination of two differently charged polypeptides, poly-L-lysine (PL) and poly-L-glutamate (PG), has shown excellent postsurgical antiadhesive properties. However, the high molecular, positively charged PL is toxic in high doses, proposed as lysis of red blood cells.
K, Isaksson, D, Akerberg, M, Posaric-Bauden, R, Andersson, B, Tingstedt   +4 more
openaire   +2 more sources

Spectral study of interaction between poly(l-lysine)–poly(ethylene glycol)–poly(l-lysine) and nucleic acids

Journal of Materials Science: Materials in Medicine, 2011
Polymer-DNA interactions have attracted considerable interests due to their important application in DNA transfection and cellular drug delivery technologies. In this work, a new detection assay for DNA is proposed with a tri-block copolymer poly(L-lysine)-poly(ethylene glycol)-poly(L-lysine) by resonance light scattering technique with the linear ...
Yu, He, Qiujun, Yan, Gongwu, Song, Juan, Chen   +3 more
openaire   +2 more sources