Results 41 to 50 of about 145,382 (250)

Evaluation of the Effect of Psyllium on the Viability of Lactobacillus Acidophilus in Alginate-Polyl Lysine Beads [PDF]

Advanced Pharmaceutical Bulletin, 2016
Purpose:Psylliumseeds are used in traditional herbal medicine to treat various disorders. Moreover, as a soluble fiber, psyllium has potential to stimulate bacterial growth in digestive system.
Jaleh Esmaeilzadeh, Hossein Nazemiyeh, Maryam Maghsoodi, Farzaneh Lotfipour   +3 more
doaj   +1 more source

Evaluation of the optimal dose for maximizing the anti-adhesion performance of a self-degradable dextran-based material

Carbohydrate Polymer Technologies and Applications, 2022
LYDEX, which is a hydrogel composed of aldehyde-functionalized dextran and succinic anhydride-treated ε-poly-L-lysine, was previously developed by our group as a self-degradable adhesive with an excellent functionality.
Woogi Hyon, Suong-Hyu Hyon, Kazuaki Matsumura   +2 more
doaj   +1 more source

Iontophoresis of Poly-L-lysines: The Role of Molecular Weight?

Pharmaceutical Research, 1997
(1) To determine the extent of iontophoretic transport as a function of molecular weight (MW) of the penetrant; and (2) to visually and quantitatively characterize the iontophoretic transport pathways (follicular (F) versus nonfollicular (NF) of the fluorescently-labeled poly-L-lysines employed.A series of fluorescently-labeled poly-L-lysines (FITC ...
Norris G., Turner, Ferry, Laura, Price, Matthew, Cullander, Christopher, Guy, Richard H.   +4 more
openaire   +2 more sources

Poly‐L‐lysine amplification of protamine immobilization and heparin adsorption [PDF]

Journal of Biomedical Materials Research, 1998
We previously reported the development of a cellulose fiber based blood filter device containing immobilized protamine (termed protamine filter) that could be used to control both heparin- and protamine-induced complications during extracorporeal therapy. To achieve enhanced heparin adsorption on the fibers, we examined the possibility of utilizing the
Zhang, Yuehua, Singh, Vijendra K., Yang, Victor C.   +2 more
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The effect of different coating substrates on the expression of integrin α 2 in Sombati epileptic cell model

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To investigate the effect of different coating substrates on the integrin α2 expression level of hippocampal neurons in Sombati epileptic cell model. Methods After coated with laminin and poly-L-lysine as substrates on the tissue culture plates
Jie SU, Yuan WU, Meigang MA, Yuejuan WU, Yun LIU, Yulan TANG, Lu YU   +6 more
doaj  

Polylysine complexes and their biomedical applications

Engineered Regeneration, 2023
Poly-L-lysine (PLL) is a water-soluble biopolymer consist of repeating unit of L-lysine. It displays intrinsic non-antigenicity, antibacterial property, biocompatibility, and biodegradability, and facile synthesis procedure, therefore has attracted ...
Haofang Zhu, Rui Liu, Yixuan Shang, Lingyun Sun   +3 more
doaj   +1 more source

Interaction and Aggregation of Sodium Aurothiomalate and Poly l-Lysine

Journal of Pharmacy and Pharmacology, 1992
Abstract This report describes the interaction and aggregation of sodium aurothiomalate with polylysine, a potentially useful property, both as a model for drug-protein interaction and as a means of reversibly immobilizing sodium aurothiomalate.
R A, Brown, T M, Wells
openaire   +2 more sources