Results 61 to 70 of about 145,382 (250)

Intracellular labeling and quantification process by magnetic resonance imaging using iron oxide magnetic nanoparticles in rat C6 glioma cell line [PDF]

Einstein (São Paulo), 2012
Objective: To assess intracellular labeling and quantification by magnetic resonance imaging using iron oxide magnetic nanoparticles coated with biocompatible materials in rat C6 glioma cells in vitro.
Edson Amaro Junior, Walter Humberto Zavala Cárdenas, Paulo Henrique Silveira, Fabiana Rossan, Tatiana Tais Sibov, Liza Aya Mabuchi Miyaki, Lorena Favaro Pavon, Javier Bustamante Mamani, Lionel Fernel Gamarra   +8 more
doaj   +2 more sources

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Poly(l-lysine) as a polychelatogen to remove toxic metals using ultrafiltration and bactericide properties of poly(l-lysine)–Cu2+ complexes

Polymer Bulletin, 2010
Poly(l-lysine) is a water-soluble, synthetic polypeptide containing functional amine groups that help remove di- and trivalent metal ions from aqueous solutions. This polymer’s removal properties were studied under different experimental conditions: (1) competitive and non-competitive conditions; (2) different pHs; and (3) filtration factors. Under the
Rivas, Bernabe L., Maureira, Antonio, Guzman, Catherine, Contreras, David, Kaim, Wolfgang, Geckeler, Kurt E.   +5 more
openaire   +3 more sources

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

Advanced Healthcare Materials, EarlyView.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko, Yannick Richter, Martyna Michalska, Piotr Paczos, Karine Tadevosyan, Daniel Uribe, Jose Carlos Rodriguez‐Cabello, Ioannis Papakonstantinou, Angel Raya   +8 more
wiley   +1 more source

Postbiotics enhance the efficacy of derivative compound mouthwash against clinical Helicobacter pylori strains

Frontiers in Cellular and Infection Microbiology
BackgroundA previous study indicated that poly L-lysine-glycerol monolaurate mouthwash reduced the virulence of Helicobacter pylori; however, these compounds are derivatives.
Rawee Teanpaisan, Nuntiya Pahumunto, Nuntiya Pahumunto   +2 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Studies on Smaller (~315 μM) Microcapsules: IV. Feasibility and Safety of Intrahepatic Implantations of Small Alginate Poly-L-Lysine Microcapsules

Cell Transplantation, 1999
The most successful transplantation site of nonencapsulated islets of Langerhans is the liver. Because usual alginate poly-L-lysine microcapsules were too large (700–1200 μm diameter) for intravascular implantations and were almost exclusively implanted ...
François A. Leblond, Ginette Simard, Nathalie Henley, Bernard Rocheleau, P.-Michel Huet, Jean-Pierre Hallé   +5 more
doaj   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Ultrasmall Poly-L-Lysine Nanoparticles

The synthesis of ultrasmall poly-L-lysine (PLL) nanoparticles remains challenging using conventional nanogel preparation methods. This study investigates how the conformation of PLL precursor chains influences the resulting nanoparticle microstructure when crosslinking is performed under dilute conditions.
Thu Phuong Le, Joachim Kohlbrecher, Paula Malo de Molina   +2 more
openaire   +1 more source