Results 11 to 20 of about 116,530,352 (255)

RNA polyadenylation sites on the genomes of microorganisms, animals, and plants. [PDF]

open access: yesPLoS ONE, 2013
Pre-messenger RNA (mRNA) 3'-end cleavage and subsequent polyadenylation strongly regulate gene expression. In comparison with the upstream or downstream motifs, relatively little is known about the feature differences of polyadenylation [poly(A)] sites ...
Xiu-Qing Li, Donglei Du
doaj   +1 more source

Uridine composition of the poly-U/UC tract of HCV RNA defines non-self recognition by RIG-I. [PDF]

open access: yesPLoS Pathogens, 2012
Viral infection of mammalian cells triggers the innate immune response through non-self recognition of pathogen associated molecular patterns (PAMPs) in viral nucleic acid.
Gretja Schnell   +3 more
doaj   +1 more source

Biophysical characterization of the strong stabilization of the RNA triplex poly(U)•poly(A)*poly(U) by 9-O-(ω-amino) alkyl ether berberine analogs. [PDF]

open access: yesPLoS ONE, 2012
Binding of two 9-O-(ω-amino) alkyl ether berberine analogs BC1 and BC2 to the RNA triplex poly(U)(•)poly(A)(*)poly(U) was studied by various biophysical techniques.Berberine analogs bind to the RNA triplex non-cooperatively.
Debipreeta Bhowmik   +4 more
doaj   +1 more source

Background-Quenched Aggregation-Induced Emission through Electrostatic Interactions for the Detection of Poly(ADP-ribose) Polymerase-1 Activity

open access: yesMolecules, 2023
Poly(ADP-ribose) polymerase-1 (PARP1) is a potential biomarker and therapeutic target for cancers that can catalyze the poly-ADP-ribosylation of nicotinamide adenine dinucleotide (NAD+) onto the acceptor proteins to form long poly(ADP-ribose) (PAR ...
Fengli Gao   +3 more
doaj   +1 more source

Regulation of coronaviral poly(A) tail length during infection. [PDF]

open access: yesPLoS ONE, 2013
The positive-strand coronavirus genome of ~30 kilobase in length and subgenomic (sg) mRNAs of shorter lengths, are 5' and 3'-co-terminal by virtue of a common 5'-capped leader and a common 3'-polyadenylated untranslated region.
Hung-Yi Wu   +3 more
doaj   +1 more source

Nucleobase-crosslinked poly(2-oxazoline) nanoparticles as paclitaxel carriers with enhanced stability and ultra-high drug loading capacity for breast cancer therapy

open access: yesAsian Journal of Pharmaceutical Sciences, 2022
Poly(2-oxazoline) (POx) has been regarded as a potential candidate for drug delivery carrier to meet the challenges of nanomedicine clinical translation, due to its excellent biocompatibility and self-assembly properties.
Si Dong   +5 more
doaj   +1 more source

Architecture of covalent bonds between filament layers to enhance performance of 3D printing biodegradable polymer blends

open access: yesPolymer Testing, 2022
Generally, the filament layer adhesion in articles 3D printed by Fused Deposition Modeling (FDM, one of 3D printing method) is completely provided by the diffusion and entanglement of molecular chains between adjacent layers.
Yang Lyu   +5 more
doaj   +1 more source

Cal Poly Humboldt Publishing Catalog [PDF]

open access: yes, 2022
A catalog of publications from Cal Poly Humboldt.
The Press at Cal Poly Humboldt,
core   +1 more source

Nanostructural Arrangements and Surface Morphology on Ureasil-Polyether Films Loaded with Dexamethasone Acetate

open access: yesNanomaterials, 2021
Ureasil-Poly(ethylene oxide) (u-PEO500) and ureasil-Poly(propylene oxide) (u-PPO400) films, unloaded and loaded with dexamethasone acetate (DMA), have been investigated by carrying out atomic force microscopy (AFM), ultrasonic force microscopy (UFM ...
João Augusto Oshiro-Junior   +4 more
doaj   +1 more source

A new yeast poly(A) polymerase complex involved in RNA quality control [PDF]

open access: yes, 2005
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Sabine Dettwiler (27038)   +36 more
core   +1 more source

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