Results 51 to 60 of about 116,530,352 (255)
Small RNA modules confer different stabilities and interact differently with multiple targets.
PLoS ONE, 2013 Bacterial Hfq-associated small regulatory RNAs (sRNAs) parallel animal microRNAs in their ability to control multiple target mRNAs. The small non-coding MicA RNA represses the expression of several genes, including major outer membrane proteins such as ...
José Marques Andrade +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
GelsAmidoxime-functionalized hydrogels are one of most promising adsorbents for high-efficiency uranium (U) extraction from seawater, but bioadhesion on their surface seriously decreases their adsorption efficiency and largely shortens their service life ...
Lang Yang +9 more
doaj +1 more source
Production and Modification of Poly(Styrene-Acrylonitrile)-Polycarbonate Nanofibers and Evaluation of its Adsorption Behavior on Uranium in Aqueous Solutions [PDF]
مجله علوم و فنون هستهای, 2019 The removal and recovery of uranium from aqueous media has been considered by many of scientists and researchers since a long time ago. In this work it has been tried to produce the nano adsorbent that be able to separate the uranium from nuclear waste ...
A Naderi +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Foams based on poly(ethylene terephthalate) nanocomposites with enhanced thermal stability
, 2012 Novel poly(ethylene terephthalate) nanocomposites have been developed, incorporating commercial bottle grade polyester and modified organoclay, which exhibit enhanced thermal and dynamic-mechanical properties and improved foaming behavior.
EAmendola +4 more
core +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2013 There exists compelling evidence that Toll-like receptor 3 (TLR3) agonists can directly affect human cancer cells. The aim of this study was to investigate anti-cancer effects of TLR3 agonist in human breast cell line.
Nastaran Alizadeh +7 more
doaj
Industrial Crops and ProductsSoy protein-based adhesives are promising alternatives to petroleum-based options for industrial applications, but still face significant challenges such as weak initial adhesion, poor water resistance, limited application range, and susceptibility to ...
Shuchuan Cao +7 more
doaj +1 more source