Results 71 to 80 of about 116,530,352 (255)

A versatile characterization of poly(N-isopropylacrylamideco- N,N'-methylene-bis-acrylamide) hydrogels for composition, mechanical strength, and rheology [PDF]

, 2013
Poly(N-isopropylacrylamide-co-N,N"-methylene-bisacrylamide) (P(NIPAAm-co-MBA)) hydrogels were prepared in water using redox initiator. The copolymer composition at high conversion (> 95%) was determined indirectly by HPLC (high performance liquid ...
Sulyok, Zsolt, Fekete, Jenő, Domján, Attila, A. Meszaros, A. Szilagyi, Chetty, A., Zs. Sulyok, V. Vargha, Szilágyi, András, Mészáros, Á., Kovács, János, J. Kovacs, A. Chetty, Vargha, Viktória, J. Fekete, A. Domjan   +15 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases [PDF]

, 2004
ATP(CTP):tRNA nucleotidyl transferases, tRNA maturing enzymes found in all organisms, and eubacterial poly(A) polymerases, enzymes involved in mRNA degradation, are so similar that until now their biochemical functions could not be distinguished by their
Keller, W., Martin, G.
core  

Pancreatic Ribonuclease-Poly G Complexes Complete Inhibition of Poly U Hydrolysis [PDF]

, 1969
Pancreatic ribonuclease forms large complexes with poly G in 0.1 M acetate buffer solutions (pH 5.4). These are largest when the ratio, of ribonuclease to poly G concentration, is slightly less than 2.
Sands, J.A., Preiss, John W.
core   +1 more source

Involutive representations of coordinate algebras and quantum spaces

Journal of High Energy Physics, 2017
We show that s u 2 $$ \mathfrak{s}\mathfrak{u}(2) $$ Lie algebras of coordinate operators related to quantum spaces with s u 2 $$ \mathfrak{s}\mathfrak{u}(2) $$ noncommutativity can be conveniently represented by SO(3)-covariant poly-differential ...
Tajron Jurić, Timothé Poulain, Jean-Christophe Wallet   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Biochemical Characterization and Degradation Pattern of a Novel Endo-Type Bifunctional Alginate Lyase AlyA from Marine Bacterium Isoptericola halotolerans

Marine Drugs, 2018
Alginate lyases are important tools to prepare oligosaccharides with various physiological activities by degrading alginate. Particularly, the bifunctional alginate lyase can efficiently hydrolyze the polysaccharide into oligosaccharides.
Benwei Zhu, Limin Ning, Yucui Jiang, Lin Ge   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Interactions, structure and properties in poly(lactic acid)/thermoplastic polymer blends [PDF]

, 2014
Blends were prepared from poly(lactic acid) (PLA) and three thermoplastics, polystyrene (PS), polycarbonate (PC) and poly(methyl methacrylate) (PMMA). Rheological and mechanical properties, structure and component interactions were determined by various ...
B. Pukanszky, Renner, Károly, B. Imre, Pukánszky, Béla, K. Renner, Imre, Balázs   +5 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source