Results 91 to 100 of about 547,441 (316)
Frontiers in Chemistry, 2018 In this paper, urea-doped ZnO (U-ZnO) is investigated as a modified electron transport layer (ETL) in inverted polymer solar cells (PSCs). Using a blend of Poly{4,8-bis[(2-ethylhexyl)oxy] benzo [1,2-b:4,5-b'] dithiophene-2,6-diyl-alt-3-fluoro-2-[(2 ...
Zongtao Wang +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Distinct roles of non-canonical poly(A) polymerases in RNA metabolism [PDF]
, 2009 Trf4p and Trf5p are non-canonical poly(A) polymerases and are part of the heteromeric protein complexes TRAMP4 and TRAMP5 that promote the degradation of aberrant and short-lived RNA substrates by interacting with the nuclear exosome. To assess the level
Schenk, L. +27 more
core +1 more source
Ultrastructural nucleolar alterations induced by an ametantrone - Poly r(A-U) complex
, 1998 The current study has documented changes in the ultrastructure as well as in the intranucleolar distribution of rDNA and rRNA in RT4 (human transitional cell bladder carcinoma) cell nucleoli following a 3-h exposure to toxic doses of 50 μM ametantrone ...
Gilloteaux, Jacques +5 more
core +2 more sources
Poly(A) . Poly(U) as Adjuvant in Cancer Treatment Distribution and Pharmacokinetics in Rabbits
Experimental Biology and Medicine, 1985 Rabbits were injected with poly(A).poly(U) and the metabolic fate and stability studied using scintigraphic techniques, radioactive counting, and subcellular fractionation. The complex has a very long lifetime (measured in days) in both liver and spleen, the major locations of concentration in the animal, with about nine times more per gram of tissue ...
A M, Michelson, D, Shaool, F, Lacour
openaire +2 more sources
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Calorimetric measurement of transition enthalpies in the polynucleotidesystem poly A-poly U
, 1967 Neumann E, Ackermann T. Calorimetric measurement of transition enthalpies in the polynucleotidesystem poly A-poly U. Journal of Physical Chemistry.
Ackermann, Theodor, Neumann, Eberhard
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FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Multifunctional poly(alkyl methacrylate) films for dental care
, 2011 Towards the evaluation of non-permanent dental coatings for their capacity to impart dental-care benefits, thin films of a homologous series of comb-like poly(alkyl methacrylate)s (ethyl to octadecyl) have been deposited, from aqueous latex formulations,
Thomas G Nevell +16 more
core +1 more source