Results 111 to 120 of about 547,441 (316)

Synthesis and post-polymerisation functionalisation of aliphatic poly(carbonate)s [PDF]

This work describes the controlled organocatalytic ring-opening polymerisation (ROP) of cyclic carbonates with pendant groups for the preparation of functional aliphatic poly(carbonate)s and poly(estercarbonate) s. Their subsequent post-polymerisation
Tempelaar, Sarah
core  

Poly-3-hydroxyalkanoate synthases from Pseudomonas putida U: Substrate specificity and ultrastructural studies

, 2007
Acknowledgments This work was supported by Grants from the Comisión Interministerial de Ciencia y Tecnología (CICYT), Madrid, España (Grants BIO2003-05309-C04-01, BIO2003-05309-C04-04 and BFU2006-15214-C03-03/BMC), Excma.
Arcos, Marcos, Sanz, Jesús, Naharro, Germán, Maestro García-Donas, María Beatriz, Luengo, José, Arias, Sagrario, Sandoval, Ángel   +6 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Investigations of rate limitation in nanostructured composite electrodes and experiments towards a 3D Li-ion microbattery

, 2011
The factors effecting discharge rate limitation within LiFePO4 composite electrode structures have been investigated. It was found that for composite electrodes containing ‘small particles’ of active material solid state processes are not necessarily ...
Johns, Phillip A., Johns, Phillip A
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Prototyping of polymer based microbioreactors: micromachining by using poly(methyl methacrylate) and poly(dimethylsiloxane) polymer materials [PDF]

, 2013
Polymers have been widely accepted as materials for the fabrication of microbioreactor prototypes. In this work, microfabrication strategies namely the micromachining and casting (soft lithography) with the use poly(methyl methacrylate) (PMMA) and poly ...
Halimoon, Hazwan, Zainal Alam, Muhd Nazrul Hisham   +1 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

FLL2 modulates Arabidopsis development and stress tolerance via polyadenylation and CPSF73 interaction

iScience
Summary: The coiled-coil protein FLL2 is known to promote liquid–liquid phase separation in the polyadenylation complex, however, the role of FLL2 in polyadenylation remains unclear.
Saiqi Hao, Danhui Zhao, Congting Ye, Haidong Qu, Xiangming Zhou, Qingshun Q. Li   +5 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source