Biomedicines, 2020 Inflammatory bowel diseases (IBDs) are chronic conditions that can benefit from the combined treatment of adenosine receptor agonists and hyaluronic acid (HA), which, binding the CD44, has pro-survival effects.
Giovanni Pallio +2 more
exaly +4 more sources
Molecules, 2021 A series of tripeptides TrpTrpPhe (1), TrpTrpTyr (2), and TrpTrpTyr[CH2N(CH3)2] (3) were synthesized, and their photophysical properties and non-covalent binding to polynucleotides were investigated.
Antonija Erben +4 more
doaj +2 more sources
Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples. [PDF]
PLoS ONE, 2017 Obtaining informative short tandem repeat (STR) profiles from degraded DNA samples is a challenging task usually undermined by locus or allele dropouts and peak-high imbalances observed in capillary electrophoresis (CE) electropherograms, especially for ...
Martín E Mautner +5 more
doaj +3 more sources
Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness [PDF]
International Journal of Molecular SciencesPolynucleotides, complex molecules composed of nucleotides, have gained attention in aesthetic medicine for their potential to regulate gene expression and promote tissue regeneration.
Kyu-Ho Yi, Sky Wong, Jovian Wan
exaly +3 more sources
An Injectable Biopolymer Hydrogel Complex (PN/HA/B3) for Facial Skin Redensification and General Rejuvenation: Clinical Report on Device Safety and Efficacy [PDF]
Journal of Functional BiomaterialsThis study evaluated the safety and effectiveness of HYDRAGEL A2, an injectable medical device containing hyaluronic acid (HA), polynucleotides (PN), and niacinamide, for improving facial skin quality.
Alexandre Porcello +6 more
doaj +2 more sources
Paeonia lactiflora Callus-Derived Polynucleotides Enhance Collagen Accumulation in Human Dermal Fibroblasts [PDF]
Journal of Functional BiomaterialsPlant-derived polynucleotides (PNs) have emerged as promising regenerative biomolecules; however, their mechanisms remain less defined than those of salmon-derived polydeoxyribonucleotides (S-PDRNs).
Soyoung Hwang +8 more
doaj +2 more sources
Tear Trough Rejuvenation With Injectable Biostimulatory Polynucleotides (VAMP) [PDF]
Plastic and Reconstructive Surgery, Global OpenSummary:. Tear trough rejuvenation presents a clinical challenge due to thin skin, superficial vasculature, and age-related volume loss. VAMP, manufactured by Prollenium, a polynucleotide-based biostimulatory injectable, is designed to support dermal ...
Noury Adel, MSc, DHM +5 more
doaj +2 more sources
Granulomatous Reactions Following the Injection of Multiple Aesthetic Microimplants: A Complication Associated with Excessive Filler Exposure in a Predisposed Patient [PDF]
ReportsBackground and Clinical Significance: Granulomatous reactions are rare but clinically significant complications of aesthetic procedures involving dermal fillers, particularly in individuals with underlying immune dysregulation.
Marjorie Garcerant Tafur +1 more
doaj +2 more sources
Supersonic Cryogenic Jet Delivery of Polynucleotides Compared With Manual Intradermal Injection [PDF]
Plastic and Reconstructive Surgery, Global OpenBackground:. This study explores an alternative method of delivering polynucleotides (PNs) using a transdermal drug delivery device instead of traditional injection methods.
Michael Kim, MD +5 more
doaj +2 more sources
A Real-World Study of Polynucleotides HPT for Treating Periorbital Hyperpigmentation [PDF]
Clinical, Cosmetic and Investigational DermatologyRaquel Amado,1 Yusra Al-Mukhtar,2 Eliana Lanza,3 Pierfrancesco Bove,4 Tristan Tan,5 Nurul Ain Abdullah,6 Gonca Gökdemir,7 Nazli Caf,8 Ayse Serap Karadag,9 Carolina Prussia,10 Maurizio Cavallini11 1Skin and Medical Cosmetics, West Malling, UK; 2Dr Yusra ...
Amado R +10 more
doaj +2 more sources