The promising potential of polynucleotide injections for knee osteoarthritis: A systematic review of literature and meta‐analysis of randomized control trials [PDF]
Journal of Experimental OrthopaedicsPurpose The present study aims to synthesize and evaluate the evidence on the effectiveness of intra‐articular polynucleotides (PNs) for knee osteoarthritis (OA). Methods In March 2024, we searched MEDLINE, Emcare, Web of Science and Cochrane Library for
Joseph Elphingstone +4 more
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Polynucleotide HPTTM-Based Hydrogels Exhibit Scavenging Activity Against Reactive Oxygen Species [PDF]
AntioxidantsThis study investigates the scavenger activity of Polynucleotide High Purification Technology (PN HPTTM), alone or in combination with hyaluronic acid (PN HPTTM + HA) against oxidative stress induced by hydrogen peroxide (H2O2). Since oxidative stress is
Maria Teresa Colangelo +3 more
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An Innovative Lip Boosting Technique Using Polynucleotides: “4-point Cannula Technique” [PDF]
Plastic and Reconstructive Surgery, Global OpenSummary:. The new concept in aesthetic medicine is heading toward regenerative medicine and the use of skin boosters in our practice, so the present case report aimed to evaluate the efficacy of injecting a polynucleotide into the lips for lip ...
Noury Adel, MSc
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Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides [PDF]
Analytical Cellular Pathology, 2013 Interactions of cationic tetrakis (N, N′, N″, N‴- tetramethyltetra-3, 4-pyridinoporphyrazinatozinc (II) (Zn (tmtppa)) with synthetic polynucleotides, poly (G-C) and poly (A-T), and calf thymus DNA have been characterized in 7.5 mM phosphate buffer of pH ...
Hamid Dezhampanah, Soghra Fyzolahjani
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Stochastic Sensing of Polynucleotides Using Patterned Nanopores
Physical Review X, 2012 The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated.
Jack A. Cohen +2 more
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Results of Shoulder Adhesive Capsulitis Treatment With the Use of Platelet Rich Plasma and Nucleotide Drugs: A Comparative Study [PDF]
Travmatologiâ i Ortopediâ Rossii, 2022 Background. Intra-articular injections of autologous platelet-rich plasma (PRP), which is a natural biological stimulant and affects various parts of the regenerative process, are often used in the treatment of adhesive capsulitis.
Alexey V. Lychagin +3 more
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Antisense Polynucleotides to Induce Exon Skipping and Method of Treating Dystrophies [PDF]
, 2023 Antisense polynucleotides and their use in pharmaceutical compositions to induce exon skipping in targeted exons of the gamma sarcoglycan gene are provided, along with methods of preventing or treating dystrophic diseases such as Limb-Girdle Muscular ...
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Applied Sciences, 2021 Polynucleotides (PN) have long been known as an effective supportive therapy for wound healing. The present study investigated whether a hydrogel formulation containing PN and hyaluronic acid (PN + HA) could promote wound healing in an in vitro model of ...
Maria Teresa Colangelo +4 more
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Topical natural-origin polynucleotides in radiation-induced skin and mucosal toxicity [PDF]
Folia Medica, 2022 Seventy to 90 percent of patients who have received radiation treatment struggle with radiation skin and mucosal toxicity. The inflicted damage to progenitor cells and local microcirculation makes it more likely that wounds, infections, and fibrosis may ...
Stefania Giudici +5 more
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Bullous striae distensae in a young patient with cardiomyopathy
Dermatology Reports, 2023 Striae distensae (SD), also known as stretch marks, are observable linear scars that appear where dermal damage has occurred as a result of prolonged stretching of the skin. The actual pathophysiology of SD is still up for debate because its origins are
Yazeed Alowairdhi +2 more
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