Results 11 to 20 of about 17,878 (213)

Uracil-Peptide-Pyrene Conjugates as Cu²⁺-Sensitive Probes Targeting DNA, RNA, and Biorelevant Model Membranes. [PDF]

Chembiochem
We introduce uracil–triazole–pyrene peptidomimetics whose tunable peptide linkers precisely control light emission, copper binding, and interactions with DNA and RNA. Fine structural adjustments unlock selective biomolecular recognition and striking metal‐ and membrane‐responsive fluorescence, paving the way for a new generation of multifunctional ...
Pavlović Saftić D, Lulić Horvat L, Piantanida I.   +2 more
europepmc   +2 more sources

Granulomatous Reactions Following the Injection of Multiple Aesthetic Microimplants: A Complication Associated with Excessive Filler Exposure in a Predisposed Patient [PDF]

Reports
Background and Clinical Significance: Granulomatous reactions are rare but clinically significant complications of aesthetic procedures involving dermal fillers, particularly in individuals with underlying immune dysregulation.
Marjorie Garcerant Tafur, Carmen Rodríguez-Cerdeira   +1 more
doaj   +2 more sources

Paeonia lactiflora Callus-Derived Polynucleotides Enhance Collagen Accumulation in Human Dermal Fibroblasts [PDF]

Journal of Functional Biomaterials
Plant-derived polynucleotides (PNs) have emerged as promising regenerative biomolecules; however, their mechanisms remain less defined than those of salmon-derived polydeoxyribonucleotides (S-PDRNs).
Soyoung Hwang, Seunghye Park, Jin Woo Lee, Mira Park, Le Anh Nguyet, Yongsung Hwang, Keunsun Ahn, Hyun-young Shin, Kuk Hui Son   +8 more
doaj   +2 more sources

Tear Trough Rejuvenation With Injectable Biostimulatory Polynucleotides (VAMP) [PDF]

Plastic and Reconstructive Surgery, Global Open
Summary:. Tear trough rejuvenation presents a clinical challenge due to thin skin, superficial vasculature, and age-related volume loss. VAMP, manufactured by Prollenium, a polynucleotide-based biostimulatory injectable, is designed to support dermal ...
Noury Adel, MSc, DHM, Amira Gindi, RNP, Nenad Stankovic, DDS, Jesper Thulesen, PhD, Jack Kolenda, MD, Ida Vega Thulesen, MS3   +5 more
doaj   +2 more sources

Supersonic Cryogenic Jet Delivery of Polynucleotides Compared With Manual Intradermal Injection [PDF]

Plastic and Reconstructive Surgery, Global Open
Background:. This study explores an alternative method of delivering polynucleotides (PNs) using a transdermal drug delivery device instead of traditional injection methods.
Michael Kim, MD, Atchima Suwanchinda, MD, PhD, Jin-Hyun Kim, MD, Inneke Jane Hidajat, MBBS, Soo Yeon Park, MD, Kyu-Ho Yi, MD, PhD   +5 more
doaj   +2 more sources

The promising potential of polynucleotide injections for knee osteoarthritis: A systematic review of literature and meta‐analysis of randomized control trials [PDF]

Journal of Experimental Orthopaedics
Purpose The present study aims to synthesize and evaluate the evidence on the effectiveness of intra‐articular polynucleotides (PNs) for knee osteoarthritis (OA). Methods In March 2024, we searched MEDLINE, Emcare, Web of Science and Cochrane Library for
Joseph Elphingstone, Michael Bowler, Pietro Conte, Giuseppe Anzillotti, Elizaveta Kon   +4 more
doaj   +2 more sources

Polynucleotide HPT^TM-Based Hydrogels Exhibit Scavenging Activity Against Reactive Oxygen Species [PDF]

Antioxidants
This study investigates the scavenger activity of Polynucleotide High Purification Technology (PN HPTTM), alone or in combination with hyaluronic acid (PN HPTTM + HA) against oxidative stress induced by hydrogen peroxide (H2O2). Since oxidative stress is
Maria Teresa Colangelo, Silvana Belletti, Stefano Guizzardi, Carlo Galli   +3 more
doaj   +2 more sources

Expert Perspectives: Evidence-Based Applications of Polynucleotides (PNs) in Aesthetic Medicine and Dermatology [PDF]

Clinical, Cosmetic and Investigational Dermatology
Nark-Kyoung Rho,1 Suneel Chilukuri,2,3 Gavin Chan,4 Michael James Kim,5 Jihye Shin,5 Atchima Suwanchinda6,7 1Leaders Dermatology Clinic, Seoul, Republic of Korea; 2Refresh Dermatology, Houston, Texas, USA; 3Department of Dermatology, Baylor College of ...
Rho NK, Chilukuri S, Chan G, Kim MJ, Shin J, Suwanchinda A   +5 more
doaj   +2 more sources

Advanced Regenerative Drainage and Immunomodulatory Protocol for Dermal Filler–Induced Skin Necrosis: A Prospective Clinical Case Series [PDF]

J Cosmet Dermatol
ABSTRACT Background The widespread use of hyaluronic acid (HA) dermal fillers has been accompanied by an increase in vascular complications, including ischemia and cutaneous necrosis. Although uncommon, filler‐induced vascular compromise represents one of the most severe adverse events in aesthetic medicine and requires immediate recognition and ...
Olivares M, Araya D, Forero E, Benoit M, Mercado V.   +4 more
europepmc   +2 more sources

An Innovative Lip Boosting Technique Using Polynucleotides: “4-point Cannula Technique” [PDF]

Plastic and Reconstructive Surgery, Global Open
Summary:. The new concept in aesthetic medicine is heading toward regenerative medicine and the use of skin boosters in our practice, so the present case report aimed to evaluate the efficacy of injecting a polynucleotide into the lips for lip ...
Noury Adel, MSc
doaj   +2 more sources