Results 21 to 30 of about 7,228 (175)

Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness [PDF]

open access: yesInternational Journal of Molecular Sciences
Kyu-Ho Yi   +2 more
exaly   +2 more sources

Dipeptides Containing Pyrene and Modified Photochemically Reactive Tyrosine: Noncovalent and Covalent Binding to Polynucleotides

open access: yesMolecules, 2023
Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben   +6 more
doaj   +1 more source

Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan

open access: yesScientific Reports, 2017
The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability.
Jia-Wei Shen   +5 more
doaj   +1 more source

Fast microwave heating-based one-step synthesis of DNA and RNA modified gold nanoparticles

open access: yesNature Communications, 2022
Simple methods for attaching polynucleotides to gold nanoparticles are of interest for simplifying conjugation in a range of applications. Here, the authors report a microwave heating-based method for the fast, one-step attachment of a range of thiolated
Mengqi Huang   +8 more
doaj   +1 more source

An Enzymatic Platform for Late‐Stage (Radio)isotope Labelling of Oligonucleotides With Methyltransferases

open access: yesAngewandte Chemie, EarlyView.
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson   +3 more
wiley   +2 more sources

Intra-articular injections of polynucleotides for joint preconditioning before the injections of bionic cross-link hyaluronic acid. Case report [PDF]

open access: yesТерапевтический архив
The article discusses intra-articular injections of polynucleotides (PN) for joint preconditioning before the injections of high-molecular-weight hyaluronic acid (HA) in the context of treating osteoarthritis (OA).
Irina S. Svintsitskaya   +2 more
doaj   +1 more source

Non-enzymatic oligonucleotide ligation in coacervate protocells sustains compartment-content coupling

open access: yesNature Communications, 2023
Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content, chemical reactions, and chassis in synthetic compartments represents a key step to the assembly
Tommaso P. Fraccia, Nicolas Martin
doaj   +1 more source

Carbethoxylation of Polynucleotides [PDF]

open access: yesEuropean Journal of Biochemistry, 1971
Diethyl pyrocarbonate has been shown to react with poly(A), poly(C) and poly(G) but poly(U) does not react. Diethyl pyrocarbonate appears to carbethoxylate amino groups on the bases. Poly(A) can bind one carbethoxy group per base but the binding capacity of poly(G) and poly(C) under non‐denaturing conditions is 0.32 and 0.23, respectively.
openaire   +2 more sources

INTRAARTICULAR KNEE JOINT INJECTION: HYALURONIC ACID VS POLYNUCLEOTIDES [PDF]

open access: yesEuromediterranean Biomedical Journal, 2013
This study is a retrospective work of ambulatorial injections in patients suffering from Class II osteoarthritis (OA) of the knee. The research was conducted from January 2012 to July 2012 in a private clinic in Benevento, Hospital Val D'Elsa ...
Luigi Meccariello
doaj   +1 more source

Interaction and Binding Modes of bis-Ruthenium(II) Complex to Synthetic DNAs

open access: yesMetals, 2016
[μ-(linker)L2(dipyrido[3,2-a:2′,3′-c]phenazine)2(phenanthroline)2Ru(II)2]2+ with linker: 1,3-bis-(4-pyridyl)-propane, L: PF6 (bis-Ru-bpp) was synthesized and their binding properties to a various polynucleotides were investigated by spectroscopy ...
Hasi Rani Barai   +3 more
doaj   +1 more source

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