Results 21 to 30 of about 11,904 (209)

Dry/Wet Cycling and the Thermodynamics and Kinetics of Prebiotic Polymer Synthesis

open access: yesLife, 2016
The endoergic nature of protein and nucleic acid assembly in aqueous media presents two questions that are fundamental to the understanding of life’s origins: (i) how did the polymers arise in an aqueous prebiotic world; and (ii) once formed in some ...
David S. Ross, David Deamer
doaj   +1 more source

Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan

open access: yesScientific Reports, 2017
The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability.
Jia-Wei Shen   +5 more
doaj   +1 more source

A metric space to study differences between polynucleotides [PDF]

open access: yes, 2003
We introduce a new metric in the space of fuzzy ...
Nieto, J.J.   +2 more
core   +1 more source

2′fluoropolynucleotide-directed Reverse Transcriptase Reactions. Effect Of Homologous Polynucleotides

open access: yes, 2015
Several homologous polynucleotides have been tested as inhibitors on the reactions catalyzed by avian myeloblastosis virus (AMV) reverse transcriptase, in the presence of polyribonucleotides and 2′fluorinated polynucleotides as templates. Polynucleotides
Juca M.B.   +3 more
core   +2 more sources

Interaction and Binding Modes of bis-Ruthenium(II) Complex to Synthetic DNAs

open access: yesMetals, 2016
[μ-(linker)L2(dipyrido[3,2-a:2′,3′-c]phenazine)2(phenanthroline)2Ru(II)2]2+ with linker: 1,3-bis-(4-pyridyl)-propane, L: PF6 (bis-Ru-bpp) was synthesized and their binding properties to a various polynucleotides were investigated by spectroscopy ...
Hasi Rani Barai   +3 more
doaj   +1 more source

Dipeptides Containing Pyrene and Modified Photochemically Reactive Tyrosine: Noncovalent and Covalent Binding to Polynucleotides

open access: yesMolecules, 2023
Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben   +6 more
doaj   +1 more source

Double standard polynucleotides: two typical alternative conformations for nucleic acids [PDF]

open access: yes, 1976
Two typical alternative conformations for double strandee polynucleotides with Watson-Crick base pairing scheme are presented. these types avoid tangling of the chains. Representative models of these types with two different views, to show the similarity
Pattabiraman, N, Sasisekharan, V
core   +3 more sources

Intra-articular injections of polynucleotides for joint preconditioning before the injections of bionic cross-link hyaluronic acid. Case report [PDF]

open access: yesТерапевтический архив
The article discusses intra-articular injections of polynucleotides (PN) for joint preconditioning before the injections of high-molecular-weight hyaluronic acid (HA) in the context of treating osteoarthritis (OA).
Irina S. Svintsitskaya   +2 more
doaj   +1 more source

Carbethoxylation of Polynucleotides [PDF]

open access: yesEuropean Journal of Biochemistry, 1971
Diethyl pyrocarbonate has been shown to react with poly(A), poly(C) and poly(G) but poly(U) does not react. Diethyl pyrocarbonate appears to carbethoxylate amino groups on the bases. Poly(A) can bind one carbethoxy group per base but the binding capacity of poly(G) and poly(C) under non‐denaturing conditions is 0.32 and 0.23, respectively.
openaire   +2 more sources

Molecular field theory of hysteresis in helix-coil transitions of polynucleotides [PDF]

open access: yes, 1973
Weisbuch G, Neumann E. Molecular field theory of hysteresis in helix-coil transitions of polynucleotides. Biopolymers. 1973;12(7):1479-1491.A molecular field theory, taking into account long-range electrostatic forces is used to study helix-coil ...
Weisbuch, G., Neumann, Eberhard
core   +1 more source

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