Results 31 to 40 of about 9,001 (206)

ANTISENSE POLYNUCLEOTIDES TO INDUCE EXON SKIPPING AND METHODS OF TREATING DYSTROPHIES [PDF]

open access: yes, 2023
Antisense polynucleotides and their use in pharmaceutical compositions to induce exon skipping in targeted exons of the gamma sarcoglycan gene are provided, along with methods of preventing or treating dystrophic diseases such as Limb-Girdle Muscular ...

core   +4 more sources

Interaction and Binding Modes of bis-Ruthenium(II) Complex to Synthetic DNAs

open access: yesMetals, 2016
[μ-(linker)L2(dipyrido[3,2-a:2′,3′-c]phenazine)2(phenanthroline)2Ru(II)2]2+ with linker: 1,3-bis-(4-pyridyl)-propane, L: PF6 (bis-Ru-bpp) was synthesized and their binding properties to a various polynucleotides were investigated by spectroscopy ...
Hasi Rani Barai   +3 more
doaj   +1 more source

Non-enzymatic oligonucleotide ligation in coacervate protocells sustains compartment-content coupling

open access: yesNature Communications, 2023
Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content, chemical reactions, and chassis in synthetic compartments represents a key step to the assembly
Tommaso P. Fraccia, Nicolas Martin
doaj   +1 more source

A Novel Classification System of Skinboosters to Support Clinical Decision Making [PDF]

open access: yesJ Cosmet Dermatol
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
Hong G   +4 more
europepmc   +2 more sources

Synthetic nanocarriers for the delivery of polynucleotides to the eye [PDF]

open access: yes, 2017
This is the accepted manuscript of the following article: Saraiva, S., Castro-López, V., Pañeda, C., & Alonso, M. (2017). Synthetic nanocarriers for the delivery of polynucleotides to the eye. European Journal Of Pharmaceutical Sciences, 103, 5-18.
Pañeda Vázquez-Prada, Covadonga   +7 more
core   +1 more source

Double stranded polynucleotides synthesized.

open access: yes, 2013
Double stranded polynucleotides synthesized.
Mei-Hua Qu (50236)   +7 more
core   +1 more source

INTRAARTICULAR KNEE JOINT INJECTION: HYALURONIC ACID VS POLYNUCLEOTIDES [PDF]

open access: yesEuromediterranean Biomedical Journal, 2013
This study is a retrospective work of ambulatorial injections in patients suffering from Class II osteoarthritis (OA) of the knee. The research was conducted from January 2012 to July 2012 in a private clinic in Benevento, Hospital Val D'Elsa ...
Luigi Meccariello
doaj   +1 more source

Intra-articular injections of polynucleotides for joint preconditioning before the injections of bionic cross-link hyaluronic acid. Case report [PDF]

open access: yesТерапевтический архив
The article discusses intra-articular injections of polynucleotides (PN) for joint preconditioning before the injections of high-molecular-weight hyaluronic acid (HA) in the context of treating osteoarthritis (OA).
Irina S. Svintsitskaya   +2 more
doaj   +1 more source

Prebiotic selection for motifs in a model of template-free elongation of polymers within compartments. [PDF]

open access: yesPLoS ONE, 2017
The transition from prelife where self-replication does not occur, to life which exhibits self-replication and evolution, has been a subject of interest for many decades. Membranes, forming compartments, seem to be a critical component of this transition
Grant Kinsler   +3 more
doaj   +1 more source

Complexation of Oligo- and Polynucleotides with Methoxyphenyl-Functionalized Imidazolium Surfactants

open access: yesPharmaceutics, 2022
Interaction between cationic surfactants and nucleic acids attracts much attention due to the possibility of using such systems for gene delivery. Herein, the lipoplexes based on cationic surfactants with imidazolium head group bearing methoxyphenyl ...
Darya A. Kuznetsova   +11 more
doaj   +1 more source

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