Results 1 to 10 of about 279,067 (313)

The Cid1 poly(U) polymerase

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2008
The Schizosaccharomyces pombe cytoplasmic protein Cid1 acts as a poly(U) polymerase (PUP). Polyadenylated actin mRNA, a target of this activity, is uridylated upon arrest in S phase and is likely to be one of many such Cid1 targets. This RNA uridylation pathway appears to be conserved, as Cid1 orthologs in Arabidopsis thaliana, Caenorhabditis elegans ...
Rissland, O, Norbury, C
openaire   +3 more sources

Two homologous EF-G proteins from Pseudomonas aeruginosa exhibit distinct functions. [PDF]

open access: yesPLoS ONE, 2013
Genes encoding two proteins corresponding to elongation factor G (EF-G) were cloned from Pseudomonas aeruginosa. The proteins encoded by these genes are both members of the EFG I subfamily. The gene encoding one of the forms of EF-G is located in the str
Stephanie O Palmer   +4 more
doaj   +1 more source

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques. [PDF]

open access: yesPLoS Pathogens, 2009
Toll-like receptor (TLR) ligands are being considered as adjuvants for the induction of antigen-specific immune responses, as in the design of vaccines.
Christiane Stahl-Hennig   +17 more
doaj   +1 more source

Suppression of hepatitis B virus through therapeutic activation of RIG-I and IRF3 signaling in hepatocytes

open access: yesiScience, 2021
Summary: Hepatitis B virus (HBV) mediates persistent infection, chronic hepatitis, and liver disease. HBV covalently closed circular (ccc)DNA is central to viral persistence such that its elimination is considered the cornerstone for HBV cure ...
Sooyoung Lee   +5 more
doaj   +1 more source

Biologycal activity of Urtica cannabina L. extract

open access: yesБюллетень сибирской медицины, 2011
The dry Urtica cannabina L. extract, containing complex of biologically active materials in different regimes introduced to mice with conducting poly-chemotherapy for the purpose of reduction in its toxicity. As a result a pathomorphological study of the
K. V. Gubin   +3 more
doaj   +1 more source

Processing and Characterization of PET Composites Reinforced With Geopolymer Concrete Waste [PDF]

open access: yesMaterials Research, 2017
In the present study, poly (ethylene terephthalate)-based composites were produced and characterized. These composites were composed by poly (ethylene terephthalate) (PET) reinforced with geopolymer concrete waste (GCW).
Ana Paula dos Santos Pereira   +4 more
doaj   +2 more sources

Identification of the Amide II Band in the cis-Amide 1-Methyluracil, in Poly(U), and in Poly(A)·Poly(U)

open access: yesJournal of Biological Chemistry, 1973
The amide II band, extensively studied in secondary trans-amides but generally reported to be absent in the infrared spectra of cis-amides, has been identified at 1417 cm-1 in the cyclic cis-amide 1-methyluracil. Specific isotopic substitution (2H, 18O, 15N) provides unambiguous evidence that the mode is an N—H bending vibration extensively coupled to ...
H T, Miles   +3 more
openaire   +2 more sources

On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules

open access: yesMolecules, 2020
Gold and silver N-heterocyclic carbenes (NHCs) are emerging for therapeutic applications. Multiple techniques are here used to unveil the mechanistic details of the binding to different biosubstrates of bis(1-(anthracen-9-ylmethyl)-3-ethylimidazol-2 ...
Francesca Binacchi   +7 more
doaj   +1 more source

Two acid RNases from Dactylis glomerata seeds. Purification, properties and effect of polyamines and lectins on their activity

open access: yesActa Societatis Botanicorum Poloniae, 2014
Two glycoproteidic acid RNases (RNase I and RNase II) were obtained and purified from the seeds of Dactylis glomerata by extraction with acetate buffer, fractionation with ammonium sulfate, ion-exchange chromatography on DEAE-cellulose, DEAE-Sphadex ...
Janina Wiśniowska   +1 more
doaj   +1 more source

Hempseed Lignanamides Rich-Fraction: Chemical Investigation and Cytotoxicity towards U-87 Glioblastoma Cells

open access: yesMolecules, 2020
The weak but noteworthy presence of (poly)phenols in hemp seeds has been long overshadowed by the essential polyunsaturated fatty acids and digestible proteins, considered responsible for their high nutritional benefits.
Ersilia Nigro   +7 more
doaj   +1 more source

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